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1.
Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies.
Anal Biochem
; 617: 114118, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33508271
2.
An LC-MS/MS method for determination of tenofovir (TFV) in human plasma following tenofovir alafenamide (TAF) administration: Development, validation, cross-validation, and use of formic acid as plasma TFV stabilizer.
Anal Biochem
; 593: 113611, 2020 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32035040
3.
The determination of human peripheral blood mononuclear cell counts using a genomic DNA standard and application in tenofovir diphosphate quantitation.
Anal Biochem
; 585: 113399, 2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31437427
4.
Evaluation of calibration curve-based approaches to predict clinical inducers and noninducers of CYP3A4 with plated human hepatocytes.
Drug Metab Dispos
; 42(9): 1379-91, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24924386
5.
Evaluation of the Effects of Meal Type and Acid-Reducing Agents on the Pharmacokinetics of Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor Agonist.
Clin Pharmacol Drug Dev
; 2024 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38346861
6.
A study of the pharmacokinetics, safety, and efficacy of bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed pregnant women with HIV.
AIDS
; 38(1): F1-F9, 2024 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37939141
7.
Gender Affirming Hormones Do Not Affect the Exposure and Efficacy of F/TDF or F/TAF for HIV Preexposure Prophylaxis: A Subgroup Analysis from the DISCOVER Trial.
Transgend Health
; 9(1): 46-52, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38312459
8.
Pharmacokinetics, pharmacodynamics, safety and tolerability of cilofexor, a novel nonsteroidal Farnesoid X receptor agonist, in healthy volunteers.
Clin Transl Sci
; 16(3): 536-547, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36573450
9.
Effect of Renal Impairment on the Pharmacokinetics of Firsocostat, an Acetyl-Coenzyme A Carboxylase Inhibitor, and Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor Agonist.
J Clin Pharmacol
; 63(5): 560-568, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36700458
10.
Evaluation of the Potential for Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions for Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor (FXR) Agonist.
Clin Pharmacokinet
; 62(4): 609-621, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36906733
11.
Effect of Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor Agonist.
J Clin Pharmacol
; 63(9): 1017-1025, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37128693
12.
Plasma Protein Binding Determination for Unstable Ester Prodrugs: Remdesivir and Tenofovir Alafenamide.
J Pharm Sci
; 112(12): 3224-3232, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37722451
13.
Pharmacokinetics, safety, and tolerability of inhaled remdesivir in healthy participants.
Clin Transl Sci
; 16(11): 2276-2288, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37688349
14.
Evaluation of pharmacokinetic/pharmacodynamic relationships of PD-0162819, a biotin carboxylase inhibitor representing a new class of antibacterial compounds, using in vitro infection models.
Antimicrob Agents Chemother
; 56(1): 124-9, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21986824
15.
The determination of Sulfobutylether ß-Cyclodextrin Sodium (SBECD) by LC-MS/MS and its application in remdesivir pharmacokinetics study for pediatric patients.
J Pharm Biomed Anal
; 212: 114646, 2022 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35180564
16.
Quantitation of intracellular triphosphate metabolites of antiretroviral agents in peripheral blood mononuclear cells (PBMCs) and corresponding cell count determinations: review of current methods and challenges.
Expert Opin Drug Metab Toxicol
; 14(8): 781-802, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30010446
17.
LC-MS/MS method development and validation for the determination of polymyxins and vancomycin in rat plasma.
J Chromatogr B Analyt Technol Biomed Life Sci
; 878(28): 2831-8, 2010 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20850394
18.
Surface modification of the channels of poly(dimethylsiloxane) microfluidic chips with polyacrylamide for fast electrophoretic separations of proteins.
Anal Chem
; 76(7): 2055-61, 2004 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15053671
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