Detalles de la búsqueda
1.
Discovery of 3, 6-disubstituted isobenzofuran-1(3H)-ones as novel inhibitors of monoamine oxidases.
Bioorg Med Chem Lett
; 67: 128748, 2022 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35472505
2.
Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors.
Bioorg Med Chem
; 29: 115878, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33246256
3.
Discovery of quinazoline-2,4(1H,3H)-dione derivatives as novel PARP-1/2 inhibitors: design, synthesis and their antitumor activity.
Org Biomol Chem
; 16(17): 3189-3202, 2018 05 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29648554
4.
Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors.
Bioorg Med Chem
; 26(8): 2186-2197, 2018 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29576270
5.
Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors.
Bioorg Med Chem
; 25(15): 4045-4054, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28622906
6.
Synthesis and Pin1 inhibitory activity of thiazole derivatives.
Bioorg Med Chem
; 24(22): 5911-5920, 2016 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27692510
7.
[2,3-Dihydro-1H-pyrrolo[3,2-c]quinoline and 2,3,5,9b-tetrahydro-1H-pyrrolo[3,2-c]-quinoline derivatives:synthesis and their inhibitory activity against Kv2.1].
Yao Xue Xue Bao
; 51(5): 762-9, 2016 05.
Artículo
en Zh
| MEDLINE | ID: mdl-29874023
8.
Discovery of 1-substituted benzyl-quinazoline-2,4(1H,3H)-dione derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors.
Bioorg Med Chem
; 23(4): 681-93, 2015 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25614115
9.
[Design, synthesis and biological evaluation of novel 3-(2-oxo-2-substituted acetamido)benzamides as PARP-1 inhibitors].
Yao Xue Xue Bao
; 50(6): 738-45, 2015 Jun.
Artículo
en Zh
| MEDLINE | ID: mdl-26521446
10.
Design, synthesis and biological evaluation of 7-nitro-1H-indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase.
Bioorg Med Chem
; 22(6): 1850-62, 2014 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24530031
11.
Stereospecific gating of functional motions in Pin1.
Proc Natl Acad Sci U S A
; 108(30): 12289-94, 2011 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-21746900
12.
[Design, synthesis and biological evaluation of novel para-substituted 1-benzyl-quinazoline-2, 4 (1H, 3H)-diones as human PARP-1 inhibitors].
Yao Xue Xue Bao
; 49(4): 497-503, 2014 Apr.
Artículo
en Zh
| MEDLINE | ID: mdl-24974467
13.
Discovery of 2-Ethoxy-5-isobutyramido-N-1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects.
J Med Chem
; 67(1): 213-233, 2024 01 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38150670
14.
[Mechanism and action characteristics studies of a quinoxalinone compound against HIV-1 replication].
Yao Xue Xue Bao
; 48(6): 860-5, 2013 Jun.
Artículo
en Zh
| MEDLINE | ID: mdl-23984519
15.
[Synthesis and activity evaluation of PARP-1 inhibitors with azaindole skeleton].
Yao Xue Xue Bao
; 48(12): 1792-9, 2013 Dec.
Artículo
en Zh
| MEDLINE | ID: mdl-24689236
16.
[Design, synthesis and biological evaluation of novel diaryl ethers bearing a pyrimidine motif as human Pin1 inhibitors].
Yao Xue Xue Bao
; 48(8): 1266-72, 2013 Aug.
Artículo
en Zh
| MEDLINE | ID: mdl-24187834
17.
An in silico investigation of Kv2.1 potassium channel: Model building and inhibitors binding sites analysis.
Mol Inform
; 42(12): e202300072, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37793122
18.
Discovery of N-Arylsulfonyl-Indole-2-Carboxamide Derivatives as Galectin-3 and Galectin-8 C-Terminal Domain Inhibitors.
ACS Med Chem Lett
; 14(9): 1257-1265, 2023 Sep 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37736168
19.
Discovery of Quinazoline-2,4(1H,3H)-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 InhibitorsâDesign, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis.
J Med Chem
; 66(20): 14095-14115, 2023 10 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37843892
20.
Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton.
Bioorg Med Chem
; 20(9): 2992-9, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22459212