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1.
A Smart Fluorescent Probe for NO Detection and Application in Myocardial Fibrosis Imaging.
Anal Chem
; 92(7): 5064-5072, 2020 04 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32122120
2.
Discovery of a cobalt complex with high MEK1 binding affinity.
Bioorg Med Chem Lett
; 27(10): 2221-2224, 2017 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28385507
3.
Rational Design of Fluorescent Phthalazinone Derivatives for One- and Two-Photon Imaging.
Chemistry
; 22(35): 12363-70, 2016 Aug 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27440529
4.
Development of novel proteasome inhibitors based on phthalazinone scaffold.
Bioorg Med Chem Lett
; 26(12): 2801-2805, 2016 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27158142
5.
Discovery of a potent and highly specific ß2 proteasome inhibitor from a library of copper complexes.
Bioorg Med Chem Lett
; 26(23): 5780-5784, 2016 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27816516
6.
Discovery of 3-benzyl-1,3-benzoxazine-2,4-dione analogues as allosteric mitogen-activated kinase kinase (MEK) inhibitors and anti-enterovirus 71 (EV71) agents.
Bioorg Med Chem
; 24(16): 3472-82, 2016 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27288186
7.
Rational design, green synthesis, and initial evaluation of a series of full-color tunable fluorescent dyes enabled by the copper-catalyzed N-arylation of 6-phenyl pyridazinones and their application in cell imaging.
Chemistry
; 19(41): 13774-82, 2013 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24038329
8.
Substituted 3-benzylcoumarins as allosteric MEK1 inhibitors: design, synthesis and biological evaluation as antiviral agents.
Molecules
; 18(5): 6057-91, 2013 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23698055
9.
Dual degradation mechanism of GPX4 degrader in induction of ferroptosis exerting anti-resistant tumor effect.
Eur J Med Chem
; 247: 115072, 2023 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36603510
10.
Nitazoxanide and related thiazolides induce cell death in cancer cells by targeting the 20S proteasome with novel binding modes.
Biochem Pharmacol
; 197: 114913, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35032461
11.
Induction of Apoptosis in Cancer Cells by Glutathione Transferase Inhibitor Mediated Hydrophobic Tagging Molecules.
ACS Med Chem Lett
; 12(5): 720-725, 2021 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34055217
12.
Structure-Activity Study of Nitazoxanide Derivatives as Novel STAT3 Pathway Inhibitors.
ACS Med Chem Lett
; 12(5): 696-703, 2021 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34055214
13.
Research progress of MEK1/2 inhibitors and degraders in the treatment of cancer.
Eur J Med Chem
; 218: 113386, 2021 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33774345
14.
Early Diagnosis of Cerebral Ischemia Reperfusion Injury and Revelation of Its Regional Development by a H3R Receptor-Directed Probe.
ACS Sens
; 6(3): 1330-1338, 2021 03 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-33653024
15.
Hybrids of MEK inhibitor and NO donor as multitarget antitumor drugs.
Eur J Med Chem
; 196: 112271, 2020 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32305784
16.
Design and synthesis of tripeptidyl furylketones as selective inhibitors against the ß5 subunit of human 20S proteasome.
Eur J Med Chem
; 192: 112160, 2020 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32146375
17.
Design, synthesis and biological evaluation of cobalt(II)-Schiff base complexes as ATP-noncompetitive MEK1 inhibitors.
J Inorg Biochem
; 195: 174-181, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30954694
18.
Design, synthesis, and biological evaluation of 4-aminopyrimidine or 4,6-diaminopyrimidine derivatives as beta amyloid cleaving enzyme-1 inhibitors.
Chem Biol Drug Des
; 93(5): 926-933, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30667164
19.
Discovery of carbazole derivatives as novel allosteric MEK inhibitors by pharmacophore modeling and virtual screening.
Eur J Med Chem
; 178: 802-817, 2019 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31252285
20.
2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl)acetamides as BACE1 inhibitors: Synthesis, biological evaluation and docking studies.
Eur J Med Chem
; 137: 462-475, 2017 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28624701