Detalles de la búsqueda
1.
MET-targeting antibody (emibetuzumab) and kinase inhibitor (merestinib) as single agent or in combination in a cancer model bearing MET exon 14 skipping.
Invest New Drugs
; 36(4): 536-544, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29188469
2.
Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study.
Invest New Drugs
; 35(3): 334-344, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28299514
3.
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
Invest New Drugs
; 31(4): 833-44, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23275061
4.
Coagulopathy after successful cardiopulmonary resuscitation following cardiac arrest: implication of the protein C anticoagulant pathway.
J Am Coll Cardiol
; 46(1): 21-8, 2005 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-15992630
5.
New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated).
Crit Care
; 9 Suppl 4: S38-45, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16168074
6.
Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies.
Crit Care
; 9(4): R331-43, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16137345
7.
Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated).
Clin Infect Dis
; 37(1): 50-8, 2003 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12830408
8.
Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis.
Thromb Haemost
; 90(4): 642-53, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-14515185
9.
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569].
Crit Care
; 8(2): R82-90, 2004 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15025782
10.
LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth.
Clin Cancer Res
; 20(23): 6059-70, 2014 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25231402
11.
Inhibition of tumor growth and metastasis in non-small cell lung cancer by LY2801653, an inhibitor of several oncokinases, including MET.
Clin Cancer Res
; 19(20): 5699-710, 2013 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23989980
12.
Troponin-I as a prognosticator of mortality in severe sepsis patients.
J Crit Care
; 25(2): 270-5, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20149590
13.
Effect of recombinant human activated protein C on the bactericidal activity of human monocytes and modulation of pro-inflammatory cytokines in the presence of antimicrobial agents.
J Antimicrob Chemother
; 59(6): 1177-81, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17428810
14.
Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever.
J Infect Dis
; 196 Suppl 2: S390-9, 2007 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17940975
15.
Effect of factor V Leiden polymorphism in severe sepsis and on treatment with recombinant human activated protein C.
Crit Care Med
; 32(5 Suppl): S239-46, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15118525
16.
Protein C/activated protein C pathway: overview of clinical trial results in severe sepsis.
Crit Care Med
; 32(5 Suppl): S194-201, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15118517
17.
Soluble thrombomodulin, plasma-derived unactivated protein C, and recombinant human activated protein C in sepsis.
Crit Care Med
; 30(5 Suppl): S318-24, 2002 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-12004254
18.
Effect of drotrecogin alfa (activated) on human endothelial cell permeability and Rho kinase signaling.
Crit Care Med
; 32(5 Suppl): S302-8, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15118535
19.
Systemic host inflammatory and coagulation response in the Dengue virus primo-infection.
Cytokine
; 27(6): 173-9, 2004 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-15304247
20.
Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia.
Blood
; 102(9): 3085-92, 2003 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12869495