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1.
Single Ascending-Dose Study To Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid in Healthy Adult Subjects.
Antimicrob Agents Chemother
; 66(4): e0210821, 2022 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35285241
2.
Advancing the Therapeutic Potential of Indoleamides for Tuberculosis.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31010860
3.
Toxicity and toxicokinetic assessment of an anti-tubercular drug pretomanid in cynomolgus monkeys.
Toxicol Rep
; 9: 927-936, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35864921
4.
Phase 1 Study of the Effects of the Tuberculosis Treatment Pretomanid, Alone and in Combination With Moxifloxacin, on the QTc Interval in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 10(6): 634-646, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33378139
5.
The conduct of in vitro studies to address time-dependent inhibition of drug-metabolizing enzymes: a perspective of the pharmaceutical research and manufacturers of America.
Drug Metab Dispos
; 37(7): 1355-70, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19359406
6.
Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery.
AAPS J
; 10(1): 178-92, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18446518
7.
Effective dosing regimen of 1-aminobenzotriazole for inhibition of antipyrine clearance in rats, dogs, and monkeys.
Drug Metab Dispos
; 30(10): 1059-62, 2002 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12228180
8.
Interaction of ritonavir on tissue distribution of a [(14)c]L-valinamide, a potent human immunodeficiency virus-1 protease inhibitor, in rats using quantitative whole-body autoradiography.
Drug Metab Dispos
; 30(11): 1164-9, 2002 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12386120
9.
Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative.
Drug Metab Dispos
; 31(9): 1170-5, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12920173
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