Detalles de la búsqueda
1.
Research progress of PROTACs for neurodegenerative diseases therapy.
Bioorg Chem
; 147: 107386, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38643565
2.
Novel 2,6-disubstituted benzofuran-3-one analogues improve cerebral ischemia/reperfusion injury via neuroprotective and antioxidative effects.
Bioorg Chem
; 132: 106346, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36638655
3.
Design, synthesis and evaluation of anti-proliferative activity of 2-aryl-4-aminoquinazoline derivatives as EGFR inhibitors.
Bioorg Chem
; 112: 104848, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33819737
4.
Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE2 Production in RAW 264.7 Cells.
Molecules
; 26(20)2021 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34684673
5.
Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors.
Bioorg Med Chem
; 28(19): 115669, 2020 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32912435
6.
Design, synthesis and biological evaluation of substituted 2-(thiophen-2-yl)-1,3,5-triazine derivatives as potential dual PI3Kα/mTOR inhibitors.
Bioorg Chem
; 95: 103525, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31887474
7.
Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators.
Bioorg Chem
; 94: 103390, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31662212
8.
Optimisation of novel 4, 8-disubstituted dihydropyrimido[5,4-b][1,4]oxazine derivatives as potent GPR 119 agonists.
J Enzyme Inhib Med Chem
; 35(1): 50-58, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31656107
9.
Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus.
BMC Cancer
; 19(1): 837, 2019 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31455317
10.
Synthesis and evaluation of novel fused pyrimidine derivatives as GPR119 agonists.
Bioorg Chem
; 86: 103-111, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30685641
11.
Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors.
Molecules
; 24(19)2019 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31547116
12.
Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30061280
13.
Design and synthesis of novel senkyunolide analogues as neuroprotective agents.
Bioorg Med Chem Lett
; 28(4): 668-672, 2018 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29370975
14.
Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.
Bioorg Med Chem
; 26(14): 4080-4087, 2018 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30100020
15.
Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer's disease: Design, synthesis and biological evaluation.
Bioorg Chem
; 81: 512-528, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30245233
16.
Design, Synthesis and Biological Evaluation of Novel Phenylsulfonylurea Derivatives as PI3K/mTOR Dual Inhibitors.
Molecules
; 23(7)2018 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29954109
17.
Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist.
Bioorg Med Chem Lett
; 27(11): 2515-2519, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28408218
18.
Nitric oxide-donating derivatives of hederacolchiside A1: Synthesis and biological evaluation in vitro and in vivo as potential anticancer agents.
Bioorg Med Chem Lett
; 27(1): 98-101, 2017 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27866816
19.
Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists.
Bioorg Med Chem
; 25(1): 254-260, 2017 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27825553
20.
Synthesis and biological evaluation of Hederacolchiside A1 derivatives as anticancer agents.
Bioorg Med Chem Lett
; 26(19): 4576-4579, 2016 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27592134