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1.
Therapeutic potential of the novel Bcl-2/Bcl-XL dual inhibitor, APG1252, alone or in combination against non-small cell lung cancer.
Mol Carcinog
; 61(11): 1031-1042, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36066010
2.
MEK or ERK inhibition effectively abrogates emergence of acquired osimertinib resistance in the treatment of epidermal growth factor receptor-mutant lung cancers.
Cancer
; 126(16): 3788-3799, 2020 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32497272
3.
Large tumor suppressor kinase 2 overexpression attenuates 5-FU-resistance in colorectal cancer via activating the JNK-MIEF1-mitochondrial division pathway.
Cancer Cell Int
; 19: 97, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31011291
4.
Downregulation of RPS15A by miR-29a-3p attenuates cell proliferation in colorectal carcinoma.
Biosci Biotechnol Biochem
; 83(11): 2057-2064, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31303129
5.
Retraction Note: Large tumor suppressor kinase 2 overexpression attenuates 5-FU-resistance in colorectal cancer via activating the JNK-MIEF1-mitochondrial division pathway.
Cancer Cell Int
; 23(1): 74, 2023 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37069630
6.
Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition.
J Biol Chem
; 291(41): 21694-21702, 2016 Oct 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27576686
7.
Correction: Expression of death receptor 4 is positively regulated by MEK/ERK/AP-1 signaling and suppressed upon MEK inhibition.
J Biol Chem
; 295(26): 8871, 2020 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32591447
8.
Mcl-1 levels critically impact the sensitivities of human colorectal cancer cells to APG-1252-M1, a novel Bcl-2/Bcl-XL dual inhibitor that induces Bax-dependent apoptosis.
Neoplasia
; 29: 100798, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35462114
9.
The confused puzzles in antineutrophil cytoplasmic antibody-associated vasculitis activity evaluation: A case report.
Clin Case Rep
; 9(7): e04497, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-34322254
10.
Inhibition of MEK5/ERK5 signaling overcomes acquired resistance to the third generation EGFR inhibitor, osimertinib, via enhancing Bim-dependent apoptosis.
Cancer Lett
; 519: 141-149, 2021 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34245854
11.
KLF13 suppresses the proliferation and growth of colorectal cancer cells through transcriptionally inhibiting HMGCS1-mediated cholesterol biosynthesis.
Cell Biosci
; 10: 76, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32523679
12.
BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1.
Cancer Res
; 80(11): 2380-2393, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32156781
13.
Co-inhibition of BET and proteasome enhances ER stress and Bim-dependent apoptosis with augmented cancer therapeutic efficacy.
Cancer Lett
; 435: 44-54, 2018 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30059709
14.
Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
Cancer Lett
; 380(2): 494-504, 2016 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27450722
15.
The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition.
Oncotarget
; 6(33): 34669-79, 2015 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26415225
16.
Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.
Cancer Lett
; 364(1): 70-8, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25937299
17.
The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5.
Oncotarget
; 6(19): 17532-42, 2015 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26009898
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