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1.
Diurnal and stress-induced intra-hippocampal corticosterone rise attenuated in 11ß-HSD1-deficient mice: a microdialysis study in young and aged mice.
Eur J Neurosci
; 41(6): 787-92, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25614240
2.
11beta-hydroxysteroid dehydrogenase type 1 deficiency prevents memory deficits with aging by switching from glucocorticoid receptor to mineralocorticoid receptor-mediated cognitive control.
J Neurosci
; 31(11): 4188-93, 2011 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-21411659
3.
11ß-Hydroxysteroid dehydrogenase 1 deficiency prevents PTSD-like memory in young adult mice.
Psychoneuroendocrinology
; 146: 105945, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36183622
4.
Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice.
J Neurosci
; 30(41): 13867-72, 2010 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-20943927
5.
11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments.
J Neurosci
; 30(20): 6916-20, 2010 May 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-20484633
6.
Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice.
J Neurosci
; 27(39): 10487-96, 2007 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17898220
7.
Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids.
Psychoneuroendocrinology
; 89: 13-22, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29306773
8.
Central administration of a cytochrome P450-7B product 7 alpha-hydroxypregnenolone improves spatial memory retention in cognitively impaired aged rats.
J Neurosci
; 26(43): 11034-40, 2006 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-17065445
9.
The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice.
Neuropsychopharmacology
; 32(12): 2520-9, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17356567
10.
Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats.
J Neurosci
; 22(4): 1436-42, 2002 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-11850470
11.
Intrahippocampal glucocorticoids generated by 11ß-HSD1 affect memory in aged mice.
Neurobiol Aging
; 36(1): 334-43, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25109766
12.
Short-term inhibition of 11ß-hydroxysteroid dehydrogenase type 1 reversibly improves spatial memory but persistently impairs contextual fear memory in aged mice.
Neuropharmacology
; 91: 71-6, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25497454
13.
Cognitive and Disease-Modifying Effects of 11ß-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease.
Endocrinology
; 156(12): 4592-603, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26305888
14.
The effect of chronic fluoxetine treatment on brain corticosteroid receptor mRNA expression and spatial memory in young and aged rats.
Brain Res Mol Brain Res
; 106(1-2): 117-23, 2002 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12393271
15.
Differential regulation of variant glucocorticoid receptor mRNAs in the rat hippocampus by the antidepressant fluoxetine.
Brain Res Mol Brain Res
; 129(1-2): 189-92, 2004 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15469896
16.
11 Beta-hydroxysteroid dehydrogenases in the brain: two enzymes two roles.
Ann N Y Acad Sci
; 1007: 357-66, 2003 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-14993069
17.
Inhibiting 11ß-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning.
Neuropharmacology
; 81: 231-6, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24495397
18.
Local amplification of glucocorticoids in the aging brain and impaired spatial memory.
Front Aging Neurosci
; 4: 24, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22952463
19.
Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl2: hippocampal signal enhancement without disruption of hippocampus-dependent behavior.
Behav Brain Res
; 216(1): 293-300, 2011 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20713092
20.
11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics.
Proc Natl Acad Sci U S A
; 101(17): 6734-9, 2004 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-15071189
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