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1.
Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.
J Biol Chem
; 285(28): 21849-57, 2010 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-20444701
2.
Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells.
Oncotarget
; 11(17): 1478-1492, 2020 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32391118
3.
The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor-Positive Metastatic Breast Cancer.
Cancer Discov
; 10(8): 1174-1193, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32404308
4.
Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.
Mol Cancer Ther
; 18(12): 2207-2219, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31530649
5.
Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene.
Cancer Discov
; 9(2): 248-263, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30373917
6.
Induction of apoptosis by sphingoid long-chain bases in Aspergillus nidulans.
Mol Cell Biol
; 23(1): 163-77, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12482970
7.
Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib.
Cancer Cell
; 32(6): 761-776.e6, 2017 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29232554
8.
Genomic alterations and molecular subtypes of gastric cancers in Asians.
Chin J Cancer
; 35: 42, 2016 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27160712
9.
A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models.
Mol Cancer Ther
; 14(11): 2463-72, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26304237
10.
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.
Nat Med
; 21(5): 449-56, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25894828
11.
Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencing.
Nat Commun
; 5: 5477, 2014 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-25407104
12.
Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity.
Mol Cancer Ther
; 13(2): 364-74, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24356814
13.
A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models.
Mol Cancer Ther
; 13(6): 1442-56, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24688048
14.
p38 mitogen-activated protein kinase promotes cell survival in response to DNA damage but is not required for the G(2) DNA damage checkpoint in human cancer cells.
Mol Cell Biol
; 30(15): 3816-26, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20516219
15.
Discovery of cercosporamide, a known antifungal natural product, as a selective Pkc1 kinase inhibitor through high-throughput screening.
Eukaryot Cell
; 3(4): 932-43, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15302826
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