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1.
Inhibition of the ATR-DNAPKcs-RB axis drives G1/S-phase transition and sensitizes triple-negative breast cancer (TNBC) to DNA holliday junctions.
Biochem Pharmacol
; 225: 116310, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38788960
2.
Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors.
J Med Chem
; 63(17): 9752-9772, 2020 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32697083
3.
Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair.
J Med Chem
; 62(6): 3147-3162, 2019 03 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30827110
4.
Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction.
J Med Chem
; 60(16): 6924-6941, 2017 08 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-28714689
5.
New Disubstituted Quindoline Derivatives Inhibiting Burkitt's Lymphoma Cell Proliferation by Impeding c-MYC Transcription.
J Med Chem
; 60(13): 5438-5454, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28603988
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