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1.
Identification of a novel heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) ligand that disrupts HnRNPA2B1/nucleic acid interactions to inhibit the MDMX-p53 axis in gastric cancer.
Pharmacol Res
; 189: 106696, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36791898
2.
A small-molecule inhibitor of MDMX suppresses cervical cancer cells via the inhibition of E6-E6AP-p53 axis.
Pharmacol Res
; 177: 106128, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35150860
3.
DNA Holliday Junction: History, Regulation and Bioactivity.
Int J Mol Sci
; 23(17)2022 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36077130
4.
Targeting G-rich sequence to regulate the transcription of murine double minute (MDM) genes in triple-negative breast cancers.
Eur J Med Chem
; 267: 116156, 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38295687
5.
PCC0208057 as a small molecule inhibitor of TRPC6 in the treatment of prostate cancer.
Front Pharmacol
; 15: 1352373, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38567350
6.
Inhibition of the ATR-DNAPKcs-RB axis drives G1/S-phase transition and sensitizes triple-negative breast cancer (TNBC) to DNA holliday junctions.
Biochem Pharmacol
; 225: 116310, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38788960
7.
Emerging function and clinical significance of extracellular vesicle noncoding RNAs in lung cancer.
Mol Ther Oncolytics
; 24: 814-833, 2022 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35317517
8.
VE-822, a novel DNA Holliday junction stabilizer, inhibits homologous recombination repair and triggers DNA damage response in osteogenic sarcomas.
Biochem Pharmacol
; 193: 114767, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34537248
9.
Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors.
J Med Chem
; 63(17): 9752-9772, 2020 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32697083
10.
Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair.
J Med Chem
; 62(6): 3147-3162, 2019 03 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30827110
11.
Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction.
J Med Chem
; 60(16): 6924-6941, 2017 08 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-28714689
12.
New Disubstituted Quindoline Derivatives Inhibiting Burkitt's Lymphoma Cell Proliferation by Impeding c-MYC Transcription.
J Med Chem
; 60(13): 5438-5454, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28603988
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