Detalles de la búsqueda
1.
Proprotein Convertase Is the Highest-Level Activator of the Alternative Complement Pathway in the Blood.
J Immunol
; 206(9): 2198-2205, 2021 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33858964
2.
Beta-Secretase 1 Recruits Amyloid-Beta Precursor Protein to ROCK2 Kinase, Resulting in Erroneous Phosphorylation and Beta-Amyloid Plaque Formation.
Int J Mol Sci
; 24(13)2023 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37445593
3.
Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation.
J Immunol
; 200(7): 2247-2252, 2018 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29475986
4.
Design and Selection of Novel C1s Inhibitors by In Silico and In Vitro Approaches.
Molecules
; 24(20)2019 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31600984
5.
MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors.
J Immunol
; 196(2): 857-65, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26673137
6.
Segment swapping aided the evolution of enzyme function: The case of uroporphyrinogen III synthase.
Proteins
; 85(1): 46-53, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27756106
7.
Dual Role of the Active Site Residues of Thermus thermophilus 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure.
Biochemistry
; 55(3): 560-74, 2016 Jan 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-26731489
8.
Soluble components of the flagellar export apparatus, FliI, FliJ, and FliH, do not deliver flagellin, the major filament protein, from the cytosol to the export gate.
Biochim Biophys Acta
; 1843(11): 2414-23, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25068520
9.
Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2.
Proc Natl Acad Sci U S A
; 109(26): 10498-503, 2012 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22691502
10.
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway.
J Biol Chem
; 288(13): 8922-34, 2013 Mar 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-23386610
11.
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.
J Biol Chem
; 287(24): 20290-300, 2012 Jun 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22511776
12.
Evolution of the concept of conformational dynamics of enzyme functions over half of a century: A personal view.
Biopolymers
; 99(4): 263-9, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23348674
13.
Inhibition of the serine proteases of the complement system.
Adv Exp Med Biol
; 735: 23-40, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23402017
14.
A Kinetic Transition Network Model Reveals the Diversity of Protein Dimer Formation Mechanisms.
Biomolecules
; 13(12)2023 11 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38136580
15.
Quantification of the zymogenicity and the substrate-induced activity enhancement of complement factor D.
Front Immunol
; 14: 1197023, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37283768
16.
Importance of aspartate residues in balancing the flexibility and fine-tuning the catalysis of human 3-phosphoglycerate kinase.
Biochemistry
; 51(51): 10197-207, 2012 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23231058
17.
Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation.
J Immunol
; 185(7): 4169-78, 2010 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20817870
18.
A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death.
Proc Natl Acad Sci U S A
; 106(24): 9731-6, 2009 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19497882
19.
Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r.
J Biol Chem
; 285(16): 11863-9, 2010 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-20178990
20.
MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity.
J Immunol
; 183(2): 1207-14, 2009 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19564340