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1.
Role of NaV1.7 in postganglionic sympathetic nerve function in human and guinea-pig arteries.
J Physiol
; 2024 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38743485
2.
Nonclinical pharmacokinetics, pharmacodynamics and safety assessment of a FLT3L-Fc molecule for cancer immunotherapy.
Toxicol Appl Pharmacol
; 483: 116837, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38278496
3.
Preclinical development of ZED8, an 89Zr immuno-PET reagent for monitoring tumor CD8 status in patients undergoing cancer immunotherapy.
Eur J Nucl Med Mol Imaging
; 50(2): 287-301, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36271158
4.
Establishment of baseline profiles of 50 bile acids in preclinical toxicity species: A comprehensive assessment of translational differences and study design considerations for biomarker development.
Toxicol Appl Pharmacol
; 443: 116008, 2022 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35378153
5.
Polysorbate 80-Induced Anaphylactoid Reaction and the Effects on Cardiovascular Function: Dose Threshold and Species Comparison.
Int J Toxicol
; 41(2): 99-107, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35245984
6.
INVESTIGATION OF THE USE OF SERUM BIOMARKERS FOR THE DETECTION OF CARDIAC DISEASE IN MARINE MAMMALS.
J Zoo Wildl Med
; 53(2): 373-382, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35758579
7.
The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.
Regul Toxicol Pharmacol
; 120: 104857, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33387566
8.
An Industry Survey With Focus on Cardiovascular Safety Pharmacology Study Design and Data Interpretation.
Int J Toxicol
; 39(4): 274-293, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32406289
9.
Discovery of two highly divergent negative-sense RNA viruses associated with the parasitic nematode, Capillaria hepatica, in wild Mus musculus from New York City.
J Gen Virol
; 100(10): 1350-1362, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31513008
10.
Correction to: Preclinical development of ZED8, an 89Zr immunoPET reagent for monitoring tumor CD8 status in patients undergoing cancer immunotherapy.
Eur J Nucl Med Mol Imaging
; 50(2): 631, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36427067
11.
Scientific and Regulatory Policy Committee Points-to-consider Paper*: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part I. Biotherapeutics.
Toxicol Pathol
; 43(7): 915-34, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25722122
12.
Scientific and Regulatory Policy Committee Points-to-consider Paper*: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part 2. Antisense Oligonucleotides.
Toxicol Pathol
; 43(7): 935-44, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25717082
13.
Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid.
Toxicol Mech Methods
; 25(3): 201-11, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25894564
14.
Nonclinical safety biomarkers of drug-induced vascular injury: current status and blueprint for the future.
Toxicol Pathol
; 42(4): 635-57, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24777748
15.
Use of animal models of human disease for nonclinical safety assessment of novel pharmaceuticals.
Toxicol Pathol
; 41(3): 508-18, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-22968286
16.
Promoting Global Health Through Pathology: Initiation of the Global Health Pathology Network.
Vet Pathol
; 55(3): 363-365, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29635993
17.
Myocardial mononuclear cell infiltrates are not associated with increased serum cardiac troponin I in cynomolgus monkeys.
Toxicol Pathol
; 40(4): 647-50, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22298795
18.
Nonclinical Pharmacokinetics and Pharmacodynamics Characterization of Anti-CD79b/CD3 T Cell-Dependent Bispecific Antibody Using a Surrogate Molecule: A Potential Therapeutic Agent for B Cell Malignancies.
Pharmaceutics
; 14(5)2022 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35631556
19.
Recommendations for the evaluation of pathology data in nonclinical safety biomarker qualification studies.
Toxicol Pathol
; 39(7): 1129-37, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22116771
20.
Characterization of xenobiotic-induced hepatocellular enzyme induction in rats: anticipated thyroid effects and unique pituitary gland findings.
Toxicol Pathol
; 39(4): 664-77, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21551028