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1.
Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors.
Neuropharmacology
; 40(8): 1010-8, 2001 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-11406192
2.
Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro.
Neuropharmacology
; 40(8): 976-83, 2001 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-11406188
3.
Total synthesis and biological properties of novel antineoplastic (chloromethyl)furanoindolines: an asymmetric hydroboration mediated synthesis of the alkylation subunits.
J Med Chem
; 37(2): 232-9, 1994 Jan 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-8295210
4.
Synthesis and evaluation of a series of novel 2-[(4-chlorophenoxy)methyl]benzimidazoles as selective neuropeptide Y Y1 receptor antagonists.
J Med Chem
; 41(15): 2709-19, 1998 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-9667962
5.
A demonstration of the intrinsic importance of stabilizing hydrophobic binding and non-covalent van der Waals contacts dominant in the non-covalent CC-1065/B-DNA binding.
Chem Biol Interact
; 73(1): 29-52, 1990.
Artículo
en Inglés
| MEDLINE | ID: mdl-2406033
6.
An alternative and convenient strategy for generation of substantial quantities of singly 5'-32P-end-labeled double-stranded DNA for binding studies: development of a protocol for examination of functional features of (+)-CC-1065 and the duocarmycins that contribute to their sequence-selective DNA alkylation properties.
Tetrahedron
; 47(14-15): 2661-82, 1991.
Artículo
en Inglés
| MEDLINE | ID: mdl-30260354
7.
[3H]N-2-(4-(N-benzamido)phenyl)propyl-2-propanesulfonamide: a novel AMPA receptor potentiator and radioligand.
J Med Chem
; 44(3): 302-4, 2001 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11462971
8.
Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists.
J Med Chem
; 40(23): 3712-4, 1997 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-9371234
9.
Biarylpropylsulfonamides as novel, potent potentiators of 2-amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic acid (AMPA) receptors.
J Med Chem
; 43(23): 4354-8, 2000 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-11087558
10.
Demonstration of a pronounced effect of noncovalent binding selectivity on the (+)-CC-1065 DNA alkylation and identification of the pharmacophore of the alkylation subunit.
Proc Natl Acad Sci U S A
; 88(4): 1431-5, 1991 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-1847523
11.
Structure-activity relationships of a series of benzothiophene-derived NPY Y1 antagonists: optimization of the C-2 side chain.
Bioorg Med Chem Lett
; 9(3): 475-80, 1999 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-10091705
12.
Site-specific prodrug activation by antibody-beta-lactamase conjugates: preclinical investigation of the efficacy and toxicity of doxorubicin delivered by antibody directed catalysis.
Bioconjug Chem
; 6(4): 440-6, 1995.
Artículo
en Inglés
| MEDLINE | ID: mdl-7578364
13.
Structure-activity relationships of a series of 1-substituted-4-methylbenzimidazole neuropeptide Y-1 receptor antagonists.
Bioorg Med Chem Lett
; 8(5): 473-6, 1998 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-9871601
14.
Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists.
Bioorg Med Chem Lett
; 9(5): 647-52, 1999 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-10201822
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