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1.
Tailoring translational strength using Kozak sequence variants improves bispecific antibody assembly and reduces product-related impurities in CHO cells.
Biotechnol Bioeng
; 117(7): 1946-1960, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32246763
2.
Role of surface exposed tryptophan as substrate generators for the antibody catalyzed water oxidation pathway.
Mol Pharm
; 10(1): 278-88, 2013 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23136850
3.
Combining regulated and constitutive protein expression significantly boosts protein expression by increasing productivity without affecting CHO cell growth.
Biotechnol Prog
; 39(3): e3337, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36878664
4.
Development of a targeted integration Chinese hamster ovary host directly targeting either one or two vectors simultaneously to a single locus using the Cre/Lox recombinase-mediated cassette exchange system.
Biotechnol Prog
; 37(4): e3140, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33666334
5.
Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position.
Biotechnol Prog
; 36(4): e2967, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31965756
6.
Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality.
Biotechnol Prog
; 34(3): 624-634, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29226566
7.
High Intracellular Seed Train BiP Levels Correlate With Poor Production Culture Performance in CHO Cells.
Biotechnol J
; 13(10): e1700746, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-29635750
8.
Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell.
Biotechnol Prog
; 29(4): 980-5, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23606666
9.
Detection of minute virus of mice using real time quantitative PCR in assessment of virus clearance during the purification of Mammalian cell substrate derived biotherapeutics.
Biologicals
; 30(4): 259-70, 2002 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-12421584
10.
The adeno-associated virus major regulatory protein Rep78-c-Jun-DNA motif complex modulates AP-1 activity.
Virology
; 314(1): 423-31, 2003 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14517094
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