Detalles de la búsqueda
1.
Tripartite motif-containing protein 31 confers protection against nonalcoholic steatohepatitis by deactivating mitogen-activated protein kinase kinase kinase 7.
Hepatology
; 77(1): 124-143, 2023 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35429173
2.
Tumor-infiltrating lymphocytes predict efficacy of immunotherapy in advanced non-small cell lung cancer: a single-center retrospective cohort study.
Acta Oncol
; 62(8): 853-860, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37377003
3.
Design, synthesis and biological evaluation of purine-based derivatives as novel JAK2/BRD4(BD2) dual target inhibitors.
Bioorg Chem
; 132: 106386, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36702002
4.
Synthesis and biological evaluation of 6-(pyrimidin-4-yl)-1H-pyrazolo[4,3-b]pyridine derivatives as novel dual FLT3/CDK4 inhibitors.
Bioorg Chem
; 121: 105669, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35180490
5.
Commensal microbiota contributes to predicting the response to immune checkpoint inhibitors in non-small-cell lung cancer patients.
Cancer Sci
; 112(8): 3005-3017, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34028936
6.
Immune checkpoint inhibitors plus anlotinib versus anlotinib alone as third-line treatment in advanced non-small-cell lung cancer: a retrospective study.
Future Oncol
; 17(31): 4091-4099, 2021 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-34254526
7.
Unpaired 3d Electrons on Atomically Dispersed Cobalt Centres in Coordination Polymers Regulate both Oxygen Reduction Reaction (ORR) Activity and Selectivity for Use in Zinc-Air Batteries.
Angew Chem Int Ed Engl
; 59(1): 286-294, 2020 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31638312
8.
Design, synthesis, and SAR study of highly potent, selective, irreversible covalent JAK3 inhibitors.
Mol Divers
; 22(2): 343-358, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29411195
9.
Discovery of (R)-5-(benzo[d][1,3]dioxol-5-yl)-7-((1-(vinylsulfonyl)pyrrolidin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (B6) as a potent Bmx inhibitor for the treatment of NSCLC.
Bioorg Med Chem Lett
; 27(17): 4171-4175, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28734581
10.
Design and Synthesis of a Highly Selective JAK3 Inhibitor for the Treatment of Rheumatoid Arthritis.
Arch Pharm (Weinheim)
; 350(11)2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28944566
11.
Efficacy of immunotherapy in HER2-mutated non-small cell lung cancer: a single-arm meta-analysis.
J Cancer Res Clin Oncol
; 150(2): 42, 2024 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38280966
12.
Efficacy and survival outcomes of alectinib vs. crizotinib in ALKpositive NSCLC patients with CNS metastases: A retrospective study.
Oncol Lett
; 27(5): 224, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38586212
13.
Discovery of 4-amino-1,6-dihydro-7H-pyrrolo[2,3-d]pyridazin-7-one derivatives as potential receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors.
Eur J Med Chem
; 265: 116076, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38171150
14.
Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents.
Eur J Med Chem
; 268: 116265, 2024 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38430854
15.
Discovery, Optimization, and Evaluation of Potent and Selective DNA-PK Inhibitors in Combination with Chemotherapy or Radiotherapy for the Treatment of Malignancies.
J Med Chem
; 67(1): 245-271, 2024 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38117951
16.
Fragment growth-based discovery of novel TNIK inhibitors for the treatment of colorectal cancer.
Eur J Med Chem
; 268: 116240, 2024 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38422698
17.
A novel chromophore reaction-based pyrrolopyrrole aza-BODIPY fluorescent probe for H2S detection and its application in food spoilage.
Food Chem
; 427: 136591, 2023 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37364314
18.
Recent Progress on Microtubule Degradation Agents.
J Med Chem
; 66(19): 13354-13368, 2023 10 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37748178
19.
Discovery and Evaluation of 3-Quinoxalin Urea Derivatives as Potent, Selective, and Orally Available ATM Inhibitors Combined with Chemotherapy for the Treatment of Cancer via Goal-Oriented Molecule Generation and Virtual Screening.
J Med Chem
; 66(14): 9495-9518, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37438997
20.
Discovery of Potent and Selective Receptor-Interacting Serine/Threonine Protein Kinase 2 (RIPK2) Inhibitors for the Treatment of Inflammatory Bowel Diseases (IBDs).
J Med Chem
; 65(13): 9312-9327, 2022 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35709396