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1.
Activity of the Novel Aminomethylcycline KBP-7072 and Comparators against 1,057 Geographically Diverse Recent Clinical Isolates from the SENTRY Surveillance Program, 2019.
Antimicrob Agents Chemother
; 66(1): e0139721, 2022 01 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34633850
2.
Design, synthesis and biological evaluations of novel farnesoid X receptor (FXR) agonists.
Bioorg Med Chem Lett
; 76: 128993, 2022 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36130662
3.
Site-Specific Conjugation of a Selenopolypeptide to Alpha-1-antitrypsin Enhances Oxidation Resistance and Pharmacological Properties.
Angew Chem Int Ed Engl
; 61(6): e202115241, 2022 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34897938
4.
In Vitro Activity of KBP-7072, a Novel Third-Generation Tetracycline, against 531 Recent Geographically Diverse and Molecularly Characterized Acinetobacter baumannii Species Complex Isolates.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32071042
5.
Nonclinical Pharmacokinetics, Protein Binding, and Elimination of KBP-7072, an Aminomethylcycline Antibiotic, in Animal Models.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32229494
6.
Prediction of Fluoroquinolone Susceptibility Directly from Whole-Genome Sequence Data by Using Liquid Chromatography-Tandem Mass Spectrometry To Identify Mutant Genotypes.
Antimicrob Agents Chemother
; 62(3)2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29263066
7.
Asymmetric transcript discovery by RNA-seq in C. elegans blastomeres identifies neg-1, a gene important for anterior morphogenesis.
PLoS Genet
; 11(4): e1005117, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25875092
8.
Regenerative phenotype in mice with a point mutation in transforming growth factor beta type I receptor (TGFBR1).
Proc Natl Acad Sci U S A
; 108(35): 14560-5, 2011 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-21841138
9.
Pharmacokinetics of the Novel Nonsteroidal Mineralocorticoid Receptor Antagonist Ocedurenone (KBP-5074) in Individuals with Moderate Hepatic Impairment.
Eur J Drug Metab Pharmacokinet
; 49(2): 229-237, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38329646
10.
A small molecule accelerates neuronal differentiation in the adult rat.
Proc Natl Acad Sci U S A
; 107(38): 16542-7, 2010 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-20823227
11.
Pharmacokinetics and Drug-Drug Interaction of Ocedurenone (KBP-5074) in vitro and in vivo.
Eur J Drug Metab Pharmacokinet
; 48(4): 397-410, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37357226
12.
Epitope-Directed Antibody Elicitation by Genetically Encoded Chemical Cross-Linking Reactivity in the Antigen.
ACS Cent Sci
; 9(6): 1229-1240, 2023 Jun 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37396855
13.
In Vitro Activity of KBP-7072 against 536 Acinetobacter baumannii Complex Isolates Collected in China.
Microbiol Spectr
; 10(1): e0147121, 2022 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-35138143
14.
The Non-Steroidal Mineralocorticoid Receptor Antagonist KBP-5074 Limits Albuminuria and has Improved Therapeutic Index Compared With Eplerenone in a Rat Model With Mineralocorticoid-Induced Renal Injury.
Front Pharmacol
; 12: 604928, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34248613
15.
In vitro activity of a novel aminomethylcycline antibacterial (KBP-7072), a third-generation tetracycline, against clinical isolates with molecularly characterized tetracycline resistance mechanisms.
JAC Antimicrob Resist
; 3(4): dlab177, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34917942
16.
In vitro activity of KHP-3757 (a novel LpxC inhibitor) and comparator agents against recent and molecularly characterized Pseudomonas aeruginosa isolates from a global surveillance program (2017-2018).
Diagn Microbiol Infect Dis
; 98(4): 115191, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32950854
17.
A novel role for the actin-binding protein drebrin in regulating opiate addiction.
Nat Commun
; 10(1): 4140, 2019 09 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31515501
18.
Favorable prognosis and high discrepancy of genetic features in surgical patients with multiple primary lung cancers.
J Thorac Cardiovasc Surg
; 155(1): 371-379.e1, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29092754
19.
Comparison of plasma to tissue DNA mutations in surgical patients with non-small cell lung cancer.
J Thorac Cardiovasc Surg
; 154(3): 1123-1131.e2, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28625771
20.
Transcriptome Analysis Reveals Novel Entry Mechanisms and a Central Role of SRC in Host Defense during High Multiplicity Mycobacterial Infection.
PLoS One
; 8(6): e65128, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23824656