Detalles de la búsqueda
1.
Paeoniflorin alleviated muscle atrophy in cancer cachexia through inhibiting TLR4/NF-κB signaling and activating AKT/mTOR signaling.
Toxicol Appl Pharmacol
; 484: 116846, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38331105
2.
A novel FAK-degrading PROTAC molecule exhibited both anti-tumor activities and efficient MDR reversal effects.
Acta Pharmacol Sin
; 2024 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38844788
3.
Carnosol analogue WK-63 alleviated cancer cachexia by inhibiting NF-κB and activating AKT pathways in muscle while inhibiting NF-κB and AMPK pathways in adipocyte.
Toxicol Appl Pharmacol
; 479: 116729, 2023 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37863360
4.
Antitumor activity of a novel Aurora A/B kinases inhibitor TY-011 against gastric cancer by inducing DNA damage.
Anticancer Drugs
; 31(5): 440-451, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32187025
5.
Design, synthesis, and structure activity relationship (SAR) studies of novel imidazo[1,2-a] pyridine derivatives as Nek2 inhibitors.
Bioorg Med Chem
; 28(23): 115775, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32992252
6.
Establishment of a mouse model of cancer cachexia with spleen deficiency syndrome and the effects of atractylenolide I.
Acta Pharmacol Sin
; 41(2): 237-248, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31341256
7.
ES2 enhances the efficacy of chemotherapeutic agents in ABCB1-overexpressing cancer cells in vitro and in vivo.
Pharmacol Res
; 129: 388-399, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29122696
8.
Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors.
Bioorg Med Chem
; 26(12): 3308-3320, 2018 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29739714
9.
Tumor-targeting efficacy of a BF211 prodrug through hydrolysis by fibroblast activation protein-α.
Acta Pharmacol Sin
; 39(3): 415-424, 2018 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-29119969
10.
Preparation of intravenous injection nanoformulation via co-assemble between cholesterylated gemcitabine and cholesterylated mPEG: enhanced cellular uptake and intracellular drug controlled release.
J Microencapsul
; 34(2): 185-194, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-28378597
11.
Design, Synthesis, and Biological Evaluation of New Cathepsin B-Sensitive Camptothecin Nanoparticles Equipped with a Novel Multifuctional Linker.
Bioconjug Chem
; 27(5): 1267-75, 2016 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-27070848
12.
Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides.
FASEB J
; 29(2): 724-32, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25384421
13.
Compound Z526 alleviates chemotherapy-induced cachectic muscle loss by ameliorating oxidative stress-driven protein metabolic imbalance and apoptosis.
Eur J Pharmacol
; 974: 176538, 2024 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38552940
14.
The discovery and optimization of novel dual inhibitors of topoisomerase II and histone deacetylase.
Bioorg Med Chem
; 21(22): 6981-95, 2013 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24095018
15.
Corylifol A ameliorates muscle atrophy by inhibiting TAOK1/p38-MAPK/FoxO3 pathway in cancer cachexia.
J Cachexia Sarcopenia Muscle
; 14(5): 2098-2113, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37439183
16.
Carnosol ameliorated cancer cachexia-associated myotube atrophy by targeting P5CS and its downstream pathways.
Front Pharmacol
; 14: 1291194, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38249348
17.
The critical role of STAT3 in biogenesis of tumor-derived exosomes with potency of inducing cancer cachexia in vitro and in vivo.
Oncogene
; 41(7): 1050-1062, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35034093
18.
GDF-15 in tumor-derived exosomes promotes muscle atrophy via Bcl-2/caspase-3 pathway.
Cell Death Discov
; 8(1): 162, 2022 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35379793
19.
Graphene-enabled wearable sensors for healthcare monitoring.
Biosens Bioelectron
; 197: 113777, 2022 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34781177
20.
Alantolactone ameliorates cancer cachexia-associated muscle atrophy mainly by inhibiting the STAT3 signaling pathway.
Phytomedicine
; 95: 153858, 2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34861585