Detalles de la búsqueda
1.
A Phase-2 NIH-sponsored Randomized Clinical Trial of Rituximab in Scleroderma-associated Pulmonary Arterial Hypertension Did Not Reach Significance for Its Endpoints: End of Story? Not So Fast!
Am J Respir Crit Care Med
; 204(2): 123-125, 2021 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33856964
2.
Metformin inhibits estrogen-dependent endometrial cancer cell growth by activating the AMPK-FOXO1 signal pathway.
Cancer Sci
; 107(12): 1806-1817, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27636742
3.
High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1.
Cell Physiol Biochem
; 40(3-4): 538-548, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27889764
4.
High uric acid directly inhibits insulin signalling and induces insulin resistance.
Biochem Biophys Res Commun
; 447(4): 707-14, 2014 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-24769205
5.
Changing cell fate in the wall of pulmonary arteries.
Sci Transl Med
; 14(643): eabq1908, 2022 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35507673
6.
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure.
Sci Transl Med
; 14(669): eabm3565, 2022 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36322626
7.
A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer.
Cell Rep
; 38(11): 110511, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35294884
8.
Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state.
Cell Metab
; 34(2): 256-268.e5, 2022 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35108513
9.
SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes.
J Am Heart Assoc
; 10(23): e020451, 2021 12 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34719264
10.
FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity.
Cell Rep
; 35(1): 108935, 2021 04 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33826891
11.
Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity.
Sci Transl Med
; 11(478)2019 02 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30728290
12.
Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells.
Mol Cell Endocrinol
; 443: 138-145, 2017 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28042024
13.
p53-Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio-oncology.
J Am Heart Assoc
; 9(15): e017247, 2020 08 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32750288
14.
AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma.
PLoS One
; 9(4): e93256, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24709998
15.
Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic ß cells.
Mol Cell Endocrinol
; 375(1-2): 89-96, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23707617
Resultados
1 -
15
de 15
1
Próxima >
>>