Detalles de la búsqueda
1.
Design, synthesis, and biological evaluation of N-(pyridin-3-yl)pyrimidin-4-amine analogues as novel cyclin-dependent kinase 2 inhibitors for cancer therapy.
Bioorg Chem
; 143: 107019, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38096683
2.
Synthesis and biological evaluation of novel 5-substituted/unsubstituted triazolothiadiazines as tubulin depolymerizing and vascular disrupting agents with promising antitumor activity.
Drug Dev Res
; 84(5): 975-987, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37089026
3.
Concise synthesis and preliminary biological evaluation of new triazolylthioacetone derivatives bearing pyridine, pyrazine, and 3,4,5-trimethoxybenzyl fragment.
Bioorg Med Chem Lett
; 66: 128721, 2022 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35398303
4.
Efficient synthesis and evaluation of novel 6-arylamino-[1,2,4]triazolo[4,3-a]pyridine derivatives as antiproliferative agents.
Bioorg Med Chem Lett
; 75: 128978, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36089111
5.
1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains.
Arch Pharm (Weinheim)
; 355(11): e2200288, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-35941525
6.
Design, synthesis and antiproliferative activity of novel 2,4-diamino-5-methyleneaminopyrimidine derivatives as potential anticancer agents.
Bioorg Med Chem Lett
; 47: 128213, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34157389
7.
Synthesis and antiproliferative evaluation of novel 8-cyclopentyl-7,8-dihydropteridin-6(5H)-one derivatives as potential anticancer agents.
Bioorg Med Chem Lett
; 31: 127684, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33197548
8.
Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
Bioorg Med Chem Lett
; 38: 127880, 2021 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33636303
9.
Development of pteridin-7(8H)-one analogues as highly potent cyclin-dependent kinase 4/6 inhibitors: Synthesis, structure-activity relationship, and biological activity.
Bioorg Chem
; 116: 105324, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34509794
10.
Synthesis and biological evaluation of novel pyrazolo[3,4-b]pyridines as cis-restricted combretastatin A-4 analogues.
Bioorg Med Chem Lett
; 30(8): 127025, 2020 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32063430
11.
Design, synthesis and biological evaluation of novel indole-based oxalamide and aminoacetamide derivatives as tubulin polymerization inhibitors.
Bioorg Med Chem Lett
; 30(2): 126816, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31753698
12.
Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors.
Bioorg Chem
; 102: 104076, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32683180
13.
Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
Bioorg Med Chem Lett
; 29(1): 22-27, 2019 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30448234
14.
Facile one-pot synthesis, antiproliferative evaluation and structure-activity relationships of 3-amino-1H-indoles and 3-amino-1H-7-azaindoles.
Bioorg Chem
; 88: 102914, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30991193
15.
Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
Bioorg Chem
; 92: 103260, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31525523
16.
Design, synthesis and antiproliferative activity of novel substituted 2-amino-7,8-dihydropteridin-6(5H)-one derivatives.
Bioorg Med Chem Lett
; 27(17): 3954-3958, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28789892
17.
Design, synthesis and biological evaluation of novel 3-alkylsulfanyl-4-amino-1,2,4-triazole derivatives.
Bioorg Med Chem Lett
; 26(15): 3679-83, 2016 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27287368
18.
Effect of Structural Relaxation on the Electronic Structure of Graphene on Hexagonal Boron Nitride.
Phys Rev Lett
; 115(18): 186801, 2015 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-26565485
19.
Energy flux and Goos-Hänchen shift in frustrated total internal reflection.
Opt Lett
; 37(9): 1526-8, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22555726
20.
Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety.
Bioorg Med Chem Lett
; 22(13): 4471-4, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22647723