Detalles de la búsqueda
1.
A quantitative systems pharmacology model of plasma kallikrein-kinin system dysregulation in hereditary angioedema.
J Pharmacokinet Pharmacodyn
; 2024 May 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38734778
2.
Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen-targeting bispecific T cell engagers for treatment of multiple myeloma.
PLoS Comput Biol
; 18(7): e1009715, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35839267
3.
Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans.
Xenobiotica
; 49(7): 852-862, 2019 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-30132394
4.
Application of unbound liver-to-plasma concentration ratio to quantitative projection of cytochrome P450-mediated drug-drug interactions using physiologically based pharmacokinetic modelling approach.
Xenobiotica
; 49(11): 1251-1259, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30516093
5.
Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism.
Pharmacogenet Genomics
; 28(1): 7-16, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-29232328
6.
Proximal Pole Scaphoid Nonunion Reconstruction With 1,2 Intercompartmental Supraretinacular Artery Vascularized Graft and Compression Screw Fixation.
J Hand Surg Am
; 43(8): 770.e1-770.e8, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29426603
7.
Delayed-Onset Digital Ischemia After Local Anesthetic With Epinephrine Injection Requiring Phentolamine Reversal.
J Hand Surg Am
; 42(6): 479.e1-479.e4, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28259566
8.
Effects of Volar Tilt, Wrist Extension, and Plate Position on Contact Between Flexor Pollicis Longus Tendon and Volar Plate.
J Hand Surg Am
; 42(12): 996-1001, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28927879
9.
Genetic and phenotypic variation in UGT2B17, a testosterone-metabolizing enzyme, is associated with BMI in males.
Pharmacogenet Genomics
; 25(5): 263-9, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25794161
10.
Variation in P450 oxidoreductase (POR) A503V and flavin-containing monooxygenase (FMO)-3 E158K is associated with minor alterations in nicotine metabolism, but does not alter cigarette consumption.
Pharmacogenet Genomics
; 24(3): 172-6, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24448396
11.
Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo.
Pharmacogenet Genomics
; 24(2): 118-28, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24305170
12.
Gene variants in CYP2C19 are associated with altered in vivo bupropion pharmacokinetics but not bupropion-assisted smoking cessation outcomes.
Drug Metab Dispos
; 42(11): 1971-7, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25187485
13.
Personalized Predictions of Glioblastoma Infiltration: Mathematical Models, Physics-Informed Neural Networks and Multimodal Scans.
ArXiv
; 2024 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38076515
14.
Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation.
Carcinogenesis
; 34(1): 93-101, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23027621
15.
Pharmacogenetics of drug dependence: role of gene variations in susceptibility and treatment.
Annu Rev Pharmacol Toxicol
; 50: 39-61, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20055697
16.
Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state.
Pharmacogenet Genomics
; 23(3): 135-41, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23344581
17.
Regulation of vitamin C transporter in the type 1 diabetic mouse bone and bone marrow.
Exp Mol Pathol
; 95(3): 298-306, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23999113
18.
CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people.
Pharmacogenet Genomics
; 22(6): 429-40, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22569203
19.
Cannabinoid receptor stimulation increases motivation for nicotine and nicotine seeking.
Addict Biol
; 17(1): 47-61, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21521420
20.
Transcanal surgical excision of an intracochlear schwannoma.
Am J Otolaryngol
; 33(6): 779-81, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22921242