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1.
Targeting Anti-TGF-ß Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach.
J Am Soc Nephrol
; 28(12): 3616-3626, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28827403
2.
A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain.
J Neurophysiol
; 111(2): 394-404, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24155005
3.
Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and neuropathic pain.
Bioorg Med Chem Lett
; 23(17): 4857-61, 2013 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23876987
4.
Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca²âº channel blockers with analgesic activity.
Bioorg Med Chem
; 20(13): 4128-39, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22626552
5.
Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imaging.
J Pharmacol Exp Ther
; 328(1): 141-51, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18931146
6.
Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
J Med Chem
; 51(6): 1904-12, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18311894
7.
Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats.
Eur J Pharmacol
; 580(3): 314-21, 2008 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-18054908
8.
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.
Bioorg Med Chem
; 16(12): 6379-86, 2008 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18501613
9.
Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats.
J Pharmacol Toxicol Methods
; 94(Pt 1): 34-43, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29684554
10.
Dissociation between post-surgical pain behaviors and spinal Fos-like immunoreactivity in the rat.
Eur J Pharmacol
; 531(1-3): 108-17, 2006 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16438960
11.
A-306989, an inhibitor of adenosine kinase, is renoprotective in rodent models of podocyte, basement membrane, and obstructive injury.
Eur J Pharmacol
; 788: 1-11, 2016 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27288879
12.
Role of central and peripheral mGluR5 receptors in post-operative pain in rats.
Pain
; 114(1-2): 195-202, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15733645
13.
Endogenous opioid mechanisms partially mediate P2X3/P2X2/3-related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain.
Br J Pharmacol
; 146(2): 180-8, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16041397
14.
Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration.
Br J Pharmacol
; 140(8): 1381-8, 2003 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-14623769
15.
Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury.
Brain Res
; 1009(1-2): 147-58, 2004 May 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-15120592
16.
Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities.
Eur J Pharmacol
; 506(2): 107-18, 2004 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15588730
17.
Optimal blood glucose levels while using insulin to minimize the size of infarction in focal cerebral ischemia.
J Neurosurg
; 101(4): 664-8, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15481723
18.
Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models.
J Pain
; 15(4): 387.e1-14, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24374196
19.
A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats.
Biochem Pharmacol
; 83(3): 406-18, 2012 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22153861
20.
Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats.
Br J Pharmacol
; 162(2): 428-40, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20880025