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1.
Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell
; 186(24): 5347-5362.e24, 2023 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37963465
2.
Structural basis of amine odorant perception by a mammal olfactory receptor.
Nature
; 618(7963): 193-200, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-37225986
3.
Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat Chem Biol
; 20(4): 484-492, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-37945893
4.
Azaphilone pigments from the marine-derived Penicillium sclerotium UJNMF 0503 and their neuroprotective potential against H2O2-induced cell apoptosis through modulating PI3K/Akt pathway.
Bioorg Chem
; 148: 107434, 2024 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38744168
5.
Design, synthesis and biological evaluation of novel (E)-2-benzylidene-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)hydrazine-1-carboxamide derivatives as α-glucosidase inhibitors.
Bioorg Med Chem Lett
; 52: 128413, 2021 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34634473
6.
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study.
Bioorg Med Chem
; 31: 115970, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33422909
7.
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Bioorg Med Chem
; 32: 116003, 2021 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33461148
8.
Diterpenoid glucosides with cystathionine γ-lyase inhibitory activity from Tinospora sinensis.
Bioorg Chem
; 116: 105400, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34627118
9.
Discovery of new 2-phenyl-1H-benzo[d]imidazole core-based potent α-glucosidase inhibitors: Synthesis, kinetic study, molecular docking, and in vivo anti-hyperglycemic evaluation.
Bioorg Chem
; 117: 105423, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34717239
10.
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel α-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation.
Bioorg Chem
; 115: 105236, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34411978
11.
A New Fusicoccane-Type Norditerpene and a New Indone from the Marine-Derived Fungus Aspergillus aculeatinus WHUF0198.
Chem Biodivers
; 18(10): e2100562, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34382347
12.
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations.
Chem Pharm Bull (Tokyo)
; 68(1): 58-63, 2020 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31685780
13.
The Flexible Loop is a New Sweetness Determinant Site of the Sweet-Tasting Protein: Characterization of Novel Sweeter Mutants of the Single-Chain Monellin (MNEI).
Chem Senses
; 44(8): 607-614, 2019 10 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-31504288
14.
Development of hydroxamate-based histone deacetylase inhibitors containing 1,2,4-oxadiazole moiety core with antitumor activities.
Bioorg Med Chem Lett
; 29(1): 15-21, 2019 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30455152
15.
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity.
J Comput Aided Mol Des
; 33(8): 775-785, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31312965
16.
Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation.
J Comput Aided Mol Des
; 33(5): 521-530, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30989573
17.
Octahydro-Protoberberine and Protoemetine-Type Alkaloids from the Stems of Alangium salviifolium and Their Cytotoxicity.
J Nat Prod
; 82(9): 2645-2652, 2019 09 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31513408
18.
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors.
Bioorg Chem
; 83: 277-288, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30391700
19.
Germacrane-type sesquiterpenoids with cytotoxic activity from Sigesbeckia orientalis.
Bioorg Chem
; 92: 103196, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31445194
20.
Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations.
Chem Pharm Bull (Tokyo)
; 67(4): 382-388, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30930442