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1.
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates.
Bioorg Med Chem Lett
; 23(7): 2181-6, 2013 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23465612
2.
Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors.
Bioorg Med Chem Lett
; 23(10): 3075-80, 2013 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23570791
3.
Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors.
Bioorg Med Chem Lett
; 23(9): 2743-9, 2013 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23522834
4.
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain.
ChemMedChem
; 8(8): 1295-313, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23794260
5.
Reductive activation of the prodrug 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119) selectively occurs in oxygen-deficient cells and overcomes O(6)-alkylguanine-DNA alkyltransferase mediated KS119 tumor cell resistance.
Biochem Pharmacol
; 79(11): 1553-61, 2010 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20005211
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