Detalles de la búsqueda
1.
Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide.
Cell
; 185(1): 131-144.e18, 2022 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34919814
2.
Design of a bifunctional pan-sarbecovirus entry inhibitor targeting the cell receptor and viral fusion protein.
J Virol
; 97(8): e0019223, 2023 08 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37578234
3.
Phosphorylation of Neurofilament Light Chain in the VLO Is Correlated with Morphine-Induced Behavioral Sensitization in Rats.
Int J Mol Sci
; 24(9)2023 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37175416
4.
In Vitro Selection and Characterization of HIV-1 Variants with Increased Resistance to LP-40, Enfuvirtide-Based Lipopeptide Inhibitor.
Int J Mol Sci
; 23(12)2022 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35743078
5.
Design of Potent Membrane Fusion Inhibitors against SARS-CoV-2, an Emerging Coronavirus with High Fusogenic Activity.
J Virol
; 94(14)2020 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32376627
6.
Therapeutic Efficacy and Resistance Selection of a Lipopeptide Fusion Inhibitor in Simian Immunodeficiency Virus-Infected Rhesus Macaques.
J Virol
; 94(15)2020 07 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32404526
7.
Monotherapy with a low-dose lipopeptide HIV fusion inhibitor maintains long-term viral suppression in rhesus macaques.
PLoS Pathog
; 15(2): e1007552, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30716118
8.
Design and Characterization of Cholesterylated Peptide HIV-1/2 Fusion Inhibitors with Extremely Potent and Long-Lasting Antiviral Activity.
J Virol
; 93(11)2019 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30867304
9.
The Tryptophan-Rich Motif of HIV-1 gp41 Can Interact with the N-Terminal Deep Pocket Site: New Insights into the Structure and Function of gp41 and Its Inhibitors.
J Virol
; 94(1)2019 12 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31619552
10.
A Membrane-Anchored Short-Peptide Fusion Inhibitor Fully Protects Target Cells from Infections of Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus.
J Virol
; 93(22)2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31462566
11.
Molecular mechanism of HIV-1 resistance to sifuvirtide, a clinical trial-approved membrane fusion inhibitor.
J Biol Chem
; 293(33): 12703-12718, 2018 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-29929981
12.
Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus.
J Biol Chem
; 293(14): 5323-5334, 2018 04 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29425101
13.
Structural and Functional Characterization of Membrane Fusion Inhibitors with Extremely Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus.
J Virol
; 92(20)2018 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30089693
14.
Design of Novel HIV-1/2 Fusion Inhibitors with High Therapeutic Efficacy in Rhesus Monkey Models.
J Virol
; 92(16)2018 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29899103
15.
Mechanism of HIV-1 Resistance to an Electronically Constrained α-Helical Peptide Membrane Fusion Inhibitor.
J Virol
; 92(7)2018 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29321334
16.
Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
PLoS Pathog
; 13(10): e1006674, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28985237
17.
Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition.
J Virol
; 91(18)2017 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28659478
18.
A Helical Short-Peptide Fusion Inhibitor with Highly Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus.
J Virol
; 91(1)2017 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27795437
19.
A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral Activity.
J Virol
; 91(11)2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28356533
20.
Enterovirus 71 induces anti-viral stress granule-like structures in RD cells.
Biochem Biophys Res Commun
; 476(4): 212-217, 2016 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27216457