Detalles de la búsqueda
1.
Prediction of Human Pharmacokinetics of E0703, a Novel Radioprotective Agent, Using Physiologically Based Pharmacokinetic Modeling and an Interspecies Extrapolation Approach.
Int J Mol Sci
; 25(5)2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38474292
2.
[The evaluation of efflux transporter model based on RNA interference technology in vitro].
Yao Xue Xue Bao
; 50(9): 1122-7, 2015 Sep.
Artículo
en Zh
| MEDLINE | ID: mdl-26757548
3.
Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in rats.
J Neuroinflammation
; 11: 112, 2014 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-24946684
4.
[Investigation of metabolic kinetics and reaction phenotyping of ligustrazin by using liver microsomes and recombinant human enzymes].
Yao Xue Xue Bao
; 49(3): 374-9, 2014 Mar.
Artículo
en Zh
| MEDLINE | ID: mdl-24961110
5.
Assessment of the roles of P-glycoprotein and cytochrome P450 in triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model.
Drug Metab Dispos
; 41(12): 2158-65, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24065861
6.
Identification and characterization of psoralen and isopsoralen as potent CYP1A2 reversible and time-dependent inhibitors in human and rat preclinical studies.
Drug Metab Dispos
; 41(11): 1914-22, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23975028
7.
[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].
Yao Xue Xue Bao
; 47(4): 459-65, 2012 Apr.
Artículo
en Zh
| MEDLINE | ID: mdl-22799027
8.
Metabolism of novel anti-HIV agent 3-cyanomethyl-4-methyl-DCK by human liver microsomes and recombinant CYP enzymes.
Acta Pharmacol Sin
; 32(10): 1276-84, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21970838
9.
[In vitro comparison of thienorphine metabolism in liver microsomes of human, Beagle dog and rat].
Yao Xue Xue Bao
; 45(1): 98-103, 2010 Jan.
Artículo
en Zh
| MEDLINE | ID: mdl-21351457
10.
[In vitro O-demethylation of rotundine by recombinant human CYP isoenzymes].
Yao Xue Xue Bao
; 45(3): 307-13, 2010 Mar.
Artículo
en Zh
| MEDLINE | ID: mdl-21351505
11.
[Metabolism of 3-cyanomethyl-4-methyl-DCK, a new anti-HIV candidate, in human intestinal microsomes].
Yao Xue Xue Bao
; 45(9): 1116-22, 2010 Sep.
Artículo
en Zh
| MEDLINE | ID: mdl-21351567
12.
Mechanistic studies of C-C bond cleavage of nitriles by dinuclear metal cryptates.
Chemistry
; 15(45): 12399-407, 2009 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19810059
13.
Determination of 4-dimethylaminophenol concentrations in dog blood using LC-ESI/MS/MS combined with precolumn derivatization.
J Chromatogr B Analyt Technol Biomed Life Sci
; 876(1): 76-82, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18993119
14.
Identification of human cytochrome P450 and UGT enzymes involved in the metabolism of ferulic acid, a major bioactive component in traditional Chinese medicines.
Chin J Nat Med
; 15(9): 695-702, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28991531
15.
A simplified model to predict P-glycoprotein interacting drugs from 3D molecular interaction field.
Int J Pharm
; 309(1-2): 109-14, 2006 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-16376035
16.
Inhibition of P-Glycoprotein and Multidrug Resistance-Associated Protein 2 Regulates the Hepatobiliary Excretion and Plasma Exposure of Thienorphine and Its Glucuronide Conjugate.
Front Pharmacol
; 7: 242, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27555820
17.
Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice.
Sci Rep
; 5: 11747, 2015 Jul 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26134275
18.
Contribution of carboxylesterase and cytochrome P450 to the bioactivation and detoxification of isocarbophos and its enantiomers in human liver microsomes.
Toxicol Sci
; 140(1): 40-8, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24752505
19.
Simultaneous determination of triptolide and its prodrug MC002 in dog blood by LC-MS/MS and its application in pharmacokinetic studies.
J Ethnopharmacol
; 150(1): 131-7, 2013 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23994469
20.
Anion recognition of chloride and bromide by a rigid dicobalt(II) cryptate.
Inorg Chem
; 47(8): 3158-65, 2008 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-18318477