Detalles de la búsqueda
1.
Kavalactone Kawain Impedes Urothelial Tumorigenesis in UPII-Mutant Ha-Ras Mice via Inhibition of mTOR Signaling and Alteration of Cancer Metabolism.
Molecules
; 28(4)2023 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36838656
2.
Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression, and autophagy.
Mol Carcinog
; 59(2): 193-201, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31782573
3.
Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation.
Cell Commun Signal
; 17(1): 25, 2019 03 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30885218
4.
Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms.
Carcinogenesis
; 39(8): 1026-1036, 2018 07 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-29762656
5.
Molecular diversity of phenothiazines: design and synthesis of phenothiazine-dithiocarbamate hybrids as potential cell cycle blockers.
Mol Divers
; 21(4): 933-942, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28785928
6.
Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin.
Molecules
; 22(3)2017 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-28335434
7.
A new brominated chalcone derivative suppresses the growth of gastric cancer cells in vitro and in vivo involving ROS mediated up-regulation of DR5 and 4 expression and apoptosis.
Toxicol Appl Pharmacol
; 309: 77-86, 2016 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27594528
8.
Neuropilin-2 expression is inhibited by secreted Wnt antagonists and its down-regulation is associated with reduced tumor growth and metastasis in osteosarcoma.
Mol Cancer
; 14: 86, 2015 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-25890345
9.
Jaridonin-induced G2/M phase arrest in human esophageal cancer cells is caused by reactive oxygen species-dependent Cdc2-tyr15 phosphorylation via ATM-Chk1/2-Cdc25C pathway.
Toxicol Appl Pharmacol
; 282(2): 227-36, 2015 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25450480
10.
ATPase Copper Transporting Beta (ATP7B) Is a Novel Target for Improving the Therapeutic Efficacy of Docetaxel by Disulfiram/Copper in Human Prostate Cancer.
Mol Cancer Ther
; 23(6): 854-863, 2024 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38417139
11.
Neddylation-dependent LSD1 destabilization inhibits the stemness and chemoresistance of gastric cancer.
Int J Biol Macromol
; 254(Pt 3): 126801, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37689288
12.
A phase I study of docetaxel plus synthetic lycopene in metastatic prostate cancer patients.
Clin Transl Med
; 14(3): e1627, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38515274
13.
Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma.
Oncogene
; 43(13): 962-975, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38355807
14.
Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.
J Clin Invest
; 134(10)2024 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38546787
15.
Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis.
Mol Cancer
; 12: 55, 2013 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-23764122
16.
The effect of gartanin, a naturally occurring xanthone in mangosteen juice, on the mTOR pathway, autophagy, apoptosis, and the growth of human urinary bladder cancer cell lines.
Nutr Cancer
; 65 Suppl 1: 68-77, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23682785
17.
Wnt Signaling and Therapeutic Resistance in Castration-Resistant Prostate Cancer.
Curr Pharmacol Rep
; 9(5): 261-274, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37994344
18.
Comprehensive analysis of cuproptosis-related genes on bladder cancer prognosis, tumor microenvironment invasion, and drug sensitivity.
Front Oncol
; 13: 1116305, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36895470
19.
Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC.
Cell Death Dis
; 14(11): 716, 2023 11 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37923740
20.
The Potent Anti-Tumor Effects of Rhodiola Drinking Are Associated with the Inhibition of the mTOR Pathway and Modification of Tumor Metabolism in the UPII-Mutant Ha-Ras Model.
Cancers (Basel)
; 15(12)2023 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37370698