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1.
PDK1:PKCα heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane.
Biophys J
; 122(11): 2301-2310, 2023 06 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36733254
2.
Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice.
J Physiol
; 600(21): 4633-4651, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36111692
3.
Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC.
Biophys J
; 120(24): 5657-5673, 2021 12 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34673053
4.
Lifelong voluntary aerobic exercise prevents age- and Western diet- induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice.
J Physiol
; 599(3): 911-925, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33103241
5.
Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with aging.
Am J Physiol Heart Circ Physiol
; 321(1): H185-H196, 2021 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34114892
6.
Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling.
Biophys J
; 113(11): 2396-2405, 2017 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29211993
7.
Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway.
Biophys J
; 110(8): 1811-1825, 2016 04 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-27119641
8.
Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module.
Biochemistry
; 55(46): 6395-6405, 2016 Nov 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27933776
9.
Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α.
Biochemistry
; 53(10): 1697-713, 2014 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-24559055
10.
Interactions of protein kinase C-α C1A and C1B domains with membranes: a combined computational and experimental study.
J Am Chem Soc
; 136(33): 11757-66, 2014 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25075641
11.
The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies.
Biochemistry
; 52(28): 4820-9, 2013 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23745598
12.
Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs.
Geroscience
; 45(1): 65-84, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35622271
13.
Assembly of membrane-bound protein complexes: detection and analysis by single molecule diffusion.
Biochemistry
; 51(8): 1638-47, 2012 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-22263647
14.
Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice.
J Appl Physiol (1985)
; 133(4): 798-813, 2022 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35952350
15.
Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin.
Hypertension
; 77(5): 1581-1590, 2021 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33719511
16.
Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans.
Hypertension
; 78(2): 499-511, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33966451
17.
Time-Efficient Inspiratory Muscle Strength Training Lowers Blood Pressure and Improves Endothelial Function, NO Bioavailability, and Oxidative Stress in Midlife/Older Adults With Above-Normal Blood Pressure.
J Am Heart Assoc
; 10(13): e020980, 2021 07 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34184544
18.
Inorganic Nitrite Supplementation Improves Endothelial Function With Aging: Translational Evidence for Suppression of Mitochondria-Derived Oxidative Stress.
Hypertension
; 77(4): 1212-1222, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33641356
19.
Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating.
PLoS One
; 15(5): e0233012, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32469878
20.
Doxorubicin-Induced Oxidative Stress and Endothelial Dysfunction in Conduit Arteries Is Prevented by Mitochondrial-Specific Antioxidant Treatment.
JACC CardioOncol
; 2(3): 475-488, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-33073250