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1.
Peposertib, a DNA-PK Inhibitor, Enhances the Anti-Tumor Efficacy of Topoisomerase II Inhibitors in Triple-Negative Breast Cancer Models.
Int J Mol Sci
; 25(10)2024 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38791158
2.
Model-based assessment of combination therapies - ranking of radiosensitizing agents in oncology.
BMC Cancer
; 23(1): 409, 2023 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37149596
3.
Exposure-response modeling improves selection of radiation and radiosensitizer combinations.
J Pharmacokinet Pharmacodyn
; 49(2): 167-178, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34623558
4.
Peptide-Based Sandwich Immunoassay for the Quantification of the Membrane Transporter Multidrug Resistance Protein 1.
Anal Chem
; 90(9): 5788-5794, 2018 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29570278
5.
Laser ablation inductively coupled plasma mass spectrometry imaging of metals in experimental and clinical Wilson's disease.
J Cell Mol Med
; 19(4): 806-14, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25704483
6.
A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation.
Am J Respir Crit Care Med
; 190(5): 522-32, 2014 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25029038
7.
Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson's disease by laser ablation inductively coupled plasma mass spectrometry.
BMC Neurosci
; 15: 98, 2014 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25142911
8.
The novel ATR inhibitor M1774 induces replication protein overexpression and broad synergy with DNA-targeted anticancer drugs.
Mol Cancer Ther
; 2024 Mar 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38466804
9.
DNA-Dependent Protein Kinase Inhibitor Peposertib Potentiates the Cytotoxicity of Topoisomerase II Inhibitors in Synovial Sarcoma Models.
Cancers (Basel)
; 16(1)2023 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38201616
10.
Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors.
Mol Cancer Ther
; 22(7): 859-872, 2023 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37079339
11.
ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.
EMBO Mol Med
; 15(8): e17313, 2023 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37491889
12.
Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90.
Bioorg Med Chem Lett
; 22(13): 4396-403, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22632933
13.
A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies.
Mol Cancer Ther
; 21(6): 859-870, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35405736
14.
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance.
Cancer Res
; 82(21): 3962-3973, 2022 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36273494
15.
Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents.
Mol Cancer Ther
; 20(8): 1431-1441, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34045232
16.
FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response.
Eur J Cancer
; 151: 136-149, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33984662
17.
Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.
Cancer Cell
; 39(4): 566-579.e7, 2021 04 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33848478
18.
DNA-PK Inhibitor, M3814, as a New Combination Partner of Mylotarg in the Treatment of Acute Myeloid Leukemia.
Front Oncol
; 10: 127, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32117773
19.
Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.
Mol Cancer Ther
; 19(5): 1091-1101, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32220971
20.
Modeling long-term tumor growth and kill after combinations of radiation and radiosensitizing agents.
Cancer Chemother Pharmacol
; 83(6): 1159-1173, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30976845