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1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors: lead optimization studies resulting in the identification of N-(1-(2-(methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide as a preclinical development candidate.
J Med Chem
; 55(6): 2882-93, 2012 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22335555
2.
Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.
J Med Chem
; 54(15): 5562-75, 2011 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21699209
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