Detalles de la búsqueda
1.
Trinucleotide mRNA Cap Analogue N6-Benzylated at the Site of Posttranscriptional m6Am Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo.
J Am Chem Soc
; 146(12): 8149-8163, 2024 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38442005
2.
An intramolecular disulphide bond in human 4E-T affects its binding to eIF4E1a protein.
Eur Biophys J
; 52(6-7): 497-510, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37798395
3.
mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.
Nucleic Acids Res
; 45(15): 8661-8675, 2017 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28666355
4.
Cap analogs modified with 1,2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential.
Nucleic Acids Res
; 44(20): 9578-9590, 2016 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27903882
5.
Diverse cap-binding properties of Drosophila eIF4E isoforms.
Biochim Biophys Acta
; 1864(10): 1292-303, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27374989
6.
Amino-Functionalized 5' Cap Analogs as Tools for Site-Specific Sequence-Independent Labeling of mRNA.
Bioconjug Chem
; 28(7): 1978-1992, 2017 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-28613834
7.
eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei.
RNA
; 20(8): 1272-86, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24962368
8.
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.
Nucleic Acids Res
; 42(16): 10245-64, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25150148
9.
Five eIF4E isoforms from Arabidopsis thaliana are characterized by distinct features of cap analogs binding.
Biochem Biophys Res Commun
; 456(1): 47-52, 2015 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25446076
10.
Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila.
Development
; 139(17): 3211-20, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22833128
11.
Phosphate-modified analogues of m(7)GTP and m(7)Gppppm(7)G-Synthesis and biochemical properties.
Bioorg Med Chem
; 23(17): 5369-81, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26264844
12.
Trypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog.
Eukaryot Cell
; 13(7): 896-908, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24839125
13.
Affinity resins containing enzymatically resistant mRNA cap analogs--a new tool for the analysis of cap-binding proteins.
RNA
; 18(7): 1421-32, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22589334
14.
Cap analogs containing 6-thioguanosine--reagents for the synthesis of mRNAs selectively photo-crosslinkable with cap-binding biomolecules.
Org Biomol Chem
; 12(27): 4841-7, 2014 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24763507
15.
Towards novel efficient and stable nuclear import signals: synthesis and properties of trimethylguanosine cap analogs modified within the 5',5'-triphosphate bridge.
Org Biomol Chem
; 12(45): 9184-99, 2014 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25296894
16.
Translation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NH.
RNA
; 17(5): 978-88, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21447710
17.
The synthesis of isopropylidene mRNA cap analogs modified with phosphorothioate moiety and their evaluation as promoters of mRNA translation.
Bioorg Med Chem Lett
; 23(13): 3753-8, 2013 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23726029
18.
Synthesis of nucleoside phosphosulfates.
Bioorg Med Chem Lett
; 22(11): 3661-4, 2012 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22572581
19.
Synthesis of biotin labelled cap analogue--incorporable into mRNA transcripts and promoting cap-dependent translation.
Org Biomol Chem
; 10(43): 8570-4, 2012 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22832840
20.
Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis.
Bioorg Med Chem
; 20(5): 1699-710, 2012 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22316555