Detalles de la búsqueda
1.
Development of a HPLC-MS/MS Method to Assess the Pharmacokinetics and Tumour Distribution of the Dimethylarginine Dimethylaminohydrolase 1 Inhibitors ZST316 and L-257 in a Xenograft Model of Triple-Negative Breast Cancer in Mice.
Molecules
; 28(24)2023 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38138547
2.
THE SPACE DIMENSION AT THE MICRO LEVEL: MASS SPECTROMETRY IMAGING OF DRUGS IN TISSUES.
Mass Spectrom Rev
; 40(3): 201-214, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32501572
3.
Pre-existing antibodies against polyethylene glycol reduce asparaginase activities on first administration of pegylated E. coli asparaginase in children with acute lymphocytic leukemia.
Haematologica
; 107(1): 49-57, 2022 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33299233
4.
Pharmacological and clinical monitoring in children with acute lymphoblastic leukemia treated with a biogeneric PEG-l-asparaginase product.
Pediatr Blood Cancer
; 69(9): e29753, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35561075
5.
Pharmacokinetic Characterization of the DDAH1 Inhibitors ZST316 and ZST152 in Mice Using a HPLC-MS/MS Method.
Molecules
; 27(3)2022 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35164277
6.
Pharmacokinetics, safety, and activity of trabectedin as first-line treatment in elderly patients who are affected by advanced sarcoma and are unfit to receive standard chemotherapy: A phase 2 study (TR1US study) from the Italian Sarcoma Group.
Cancer
; 126(21): 4726-4734, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32749681
7.
Therapeutic Drug Monitoring of Asparaginase: Intra-individual Variability and Predictivity in Children With Acute Lymphoblastic Leukemia Treated With PEG-Asparaginase in the AIEOP-BFM Acute Lymphoblastic Leukemia 2009 Study.
Ther Drug Monit
; 42(3): 435-444, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32022785
8.
Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study.
Haematologica
; 104(9): 1812-1821, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30705097
9.
Trabectedin and olaparib in patients with advanced and non-resectable bone and soft-tissue sarcomas (TOMAS): an open-label, phase 1b study from the Italian Sarcoma Group.
Lancet Oncol
; 19(10): 1360-1371, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30217671
10.
Tumor progression and metastatic dissemination in ovarian cancer after dose-dense or conventional paclitaxel and cisplatin plus bevacizumab.
Int J Cancer
; 143(9): 2187-2199, 2018 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29752717
11.
Therapeutic Drug Monitoring of Asparaginase Activity-Method Comparison of MAAT and AHA Test Used in the International AIEOP-BFM ALL 2009 Trial.
Ther Drug Monit
; 40(1): 93-102, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29210976
12.
Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy.
Neurobiol Dis
; 99: 12-23, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-27939857
13.
High Penetration of Paclitaxel in Abdominal Wall of Rabbits after Hyperthermic Intraperitoneal Administration of Nab-Paclitaxel Compared to Standard Paclitaxel Formulation.
Pharm Res
; 34(6): 1180-1186, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28247168
14.
PEGylated Nanoparticles Obtained through Emulsion Polymerization as Paclitaxel Carriers.
Mol Pharm
; 13(1): 40-6, 2016 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26623665
15.
Phase ib of sorafenib in combination with everolimus in patients with advanced solid tumors, selected on the basis of molecular targets.
Oncologist
; 19(4): 344-5, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24674875
16.
Venetoclax penetrates in cerebrospinal fluid and may be effective in chronic lymphocytic leukemia with central nervous system involvement.
Haematologica
; 104(5): e222-e223, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30765472
17.
Immediate cooling does not prevent the ex vivo hydrolysis of L-asparagine by asparaginase.
Ther Drug Monit
; 36(4): 549-52, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24342897
18.
Validated LC-MS/MS Assay for the Quantitative Determination of Fenretinide in Plasma and Tumor and Its Application in a Pharmacokinetic Study in Mice of a Novel Oral Nanoformulation of Fenretinide.
Pharmaceutics
; 16(3)2024 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38543281
19.
Preclinical Activity of Two Paclitaxel Nanoparticle Formulations After Intraperitoneal Administration in Ovarian Cancer Murine Xenografts.
Int J Nanomedicine
; 19: 429-440, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38260242
20.
Four Additional Doses of PEG-L-Asparaginase During the Consolidation Phase in the AIEOP-BFM ALL 2009 Protocol Do Not Improve Outcome and Increase Toxicity in High-Risk ALL: Results of a Randomized Study.
J Clin Oncol
; 42(8): 915-926, 2024 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38096462