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1.
An efficient method for the preparative isolation and purification of alkaloids from Gelsemium by using high speed counter-current chromatography and preparative HPLC.
Prep Biochem Biotechnol
; : 1-11, 2024 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38592940
2.
A high-resolution mass spectrometric approach to a qualitative and quantitative comparative metabolism of the humantenine-type alkaloid rankinidine.
Rapid Commun Mass Spectrom
; 36(12): e9302, 2022 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35344234
3.
Excretion, Metabolism, and Tissue Distribution of Gelsemium elegans (Gardn. & Champ.) Benth in Pigs.
Molecules
; 27(8)2022 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35458803
4.
Characterization of N-methylcanadine and N-methylstylopine metabolites in rat liver S9 by high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
Rapid Commun Mass Spectrom
; 32(23): 2047-2054, 2018 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30252168
5.
Characterization of in vitro metabolites of three tetrahydroprotoberberine alkaloids in rat liver S9 by high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
Rapid Commun Mass Spectrom
; 32(17): 1540-1548, 2018 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29935083
6.
Comparative Analysis of the Gelsemium Alkaloids Metabolism in Human, Pig, Goat, and Rat Liver Microsomes.
Curr Drug Metab
; 2024 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38571358
7.
Effect of cytochrome P450 3A4 on tissue distribution of humantenmine, koumine, and gelsemine, three alkaloids from the toxic plant Gelsemium.
Toxicol Lett
; 397: 34-41, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38734219
8.
Protocol to characterize target components of Gelsemium using an in-house herb database and high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
STAR Protoc
; 4(3): 102510, 2023 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37578866
9.
Network Pharmacology and Experimental Verification to Unveil the Mechanism of N-Methyl-D-Aspartic Acid Rescue Humantenirine-Induced Excitotoxicity.
Metabolites
; 13(2)2023 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36837814
10.
Two-Dimensional Liquid Chromatography Method for the Determination of Gelsemium Alkaloids in Honey.
Foods
; 11(18)2022 Sep 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36141017
11.
A Proteomics Study of the Subacute Toxicity of Rat Brain after Long- Term Exposure of Gelsemium elegans.
Curr Mol Pharmacol
; 15(5): 794-801, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-34886788
12.
Sex Differences in the In Vivo Exposure Process of Multiple Components of Gelsemium elegans in Rats.
Metabolites
; 13(1)2022 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36676958
13.
Phosphoproteomics reveals NMDA receptor-mediated excitotoxicity as a key signaling pathway in the toxicity of gelsenicine.
Food Chem Toxicol
; 156: 112507, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34389372
14.
An integrated strategy toward comprehensive characterization and quantification of multiple components from herbal medicine: An application study in Gelsemium elegans.
Chin Herb Med
; 13(1): 17-32, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36117759
15.
Metabolic profile and tissue distribution of Humantenirine, an oxindole alkaloid from Gelsemium, after oral administration in rats.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1181: 122901, 2021 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34433122
16.
In vitro Metabolism of Humantenine in Liver Microsomes from Human, Pig, Goat and Rat.
Curr Drug Metab
; 22(10): 795-7801, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34468296
17.
A comprehensive toxicity evaluation in rats after long-term oral Gelsemium elegans exposure.
Biomed Pharmacother
; 137: 111284, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33561641
18.
Characterization of absorbed and produced constituents in goat plasma urine and faeces from the herbal medicine Gelsemium elegans by using high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.
J Ethnopharmacol
; 252: 112617, 2020 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31988014
19.
The Metabolism and Disposition of Koumine, Gelsemine and Humantenmine from Gelsemium.
Curr Drug Metab
; 20(7): 583-591, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31203797
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