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1.
Comprehensive evaluation of liver microsomal cytochrome P450 3A (CYP3A) inhibition: comparison of cynomolgus monkey and human.
Xenobiotica
; 47(6): 470-478, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27498589
2.
Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen.
Rapid Commun Mass Spectrom
; 25(9): 1231-40, 2011 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21488121
3.
Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11ß-hydroxydehydrogenase 1 (11ß-HSD1).
Bioorg Med Chem Lett
; 21(22): 6693-8, 2011 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21983444
4.
Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection.
J Med Chem
; 63(23): 14740-14760, 2020 12 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33226226
5.
A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen.
Rapid Commun Mass Spectrom
; 23(11): 1579-91, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19399765
6.
An automated liquid chromatography-mass spectrometry process to determine metabolic stability half-life and intrinsic clearance of drug candidates by substrate depletion.
Assay Drug Dev Technol
; 6(1): 121-9, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18336089
7.
Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR).
Bioorg Med Chem Lett
; 18(14): 3974-7, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18583127
8.
An automated high throughput liquid chromatography-mass spectrometry process to assess the metabolic stability of drug candidates.
Assay Drug Dev Technol
; 5(2): 247-64, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17477833
9.
Utility of high-resolution accurate MS to eliminate interferences in the bioanalysis of ribavirin and its phosphate metabolites.
Bioanalysis
; 4(15): 1895-905, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22943620
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