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1.
The European Lead Factory: Results from a decade of collaborative, public-private, drug discovery programs.
Drug Discov Today
; 29(3): 103886, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38244673
2.
On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.
Anal Bioanal Chem
; 403(2): 367-75, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22227812
3.
The European Lead Factory: An updated HTS compound library for innovative drug discovery.
Drug Discov Today
; 26(10): 2406-2413, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33892142
4.
A pragmatic regulatory approach for complex generics through the U.S. FDA 505(j) or 505(b)(2) approval pathways.
Ann N Y Acad Sci
; 1502(1): 5-13, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34296458
5.
Structural elucidation of biologically active neomycin N-octyl derivatives in a regioisomeric mixture by means of liquid chromatography/ion trap time-of-flight mass spectrometry.
Rapid Commun Mass Spectrom
; 24(10): 1439-46, 2010 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-20411583
6.
Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS.
Anal Bioanal Chem
; 398(4): 1771-80, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20730527
7.
Report of the AAPS Guidance Forum on the FDA Draft Guidance for Industry: "Drug Products, Including Biological Products, that Contain Nanomaterials".
AAPS J
; 21(4): 56, 2019 04 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-30997588
8.
Trimethoprim: novel reactive intermediates and bioactivation pathways by cytochrome p450s.
Chem Res Toxicol
; 21(11): 2181-7, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18816075
9.
Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites.
Chem Biol Interact
; 171(1): 96-107, 2008 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-17996858
10.
Corrigendum to "The European Lead Factory: An updated HTS compound library for innovative drug discovery" [Drug Discov. Today 26(10) (2021) 2406-2413].
Drug Discov Today
; 28(8): 103257, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35398021
11.
Automated detection of covalent adducts to human serum albumin by immunoaffinity chromatography, on-line solution phase digestion and liquid chromatography-mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 859(2): 147-56, 2007 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17913598
12.
Equivalence of complex drug products: advances in and challenges for current regulatory frameworks.
Ann N Y Acad Sci
; 1407(1): 39-49, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28445611
13.
Selective quantitative bioanalysis of proteins in biological fluids by on-line immunoaffinity chromatography-protein digestion-liquid chromatography-mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 830(2): 262-9, 2006 Jan 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-16311081
14.
The European Lead Factory: A Blueprint for Public-Private Partnerships in Early Drug Discovery.
Front Med (Lausanne)
; 3: 75, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-28154815
15.
The similarity question for biologicals and non-biological complex drugs.
Eur J Pharm Sci
; 76: 10-7, 2015 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-25912826
16.
Editorial: Public-Private Partnerships as Drivers of Innovation in Healthcare.
Front Med (Lausanne)
; 6: 114, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31214590
17.
Different pharmaceutical products need similar terminology.
AAPS J
; 16(1): 11-4, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24065599
18.
How to regulate nonbiological complex drugs (NBCD) and their follow-on versions: points to consider.
AAPS J
; 16(1): 15-21, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24065600
19.
High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS detection for the structural characterization and quantification of halogen containing drug metabolites.
Anal Chim Acta
; 698(1-2): 69-76, 2011 Jul 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-21645661
20.
Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR.
J Chromatogr B Analyt Technol Biomed Life Sci
; 878(7-8): 667-74, 2010 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20149764
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