Detalles de la búsqueda
1.
Repurposing of rabeprazole as an anti-Trypanosoma cruzi drug that targets cellular triosephosphate isomerase.
J Enzyme Inhib Med Chem
; 38(1): 2231169, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37401012
2.
Human Triosephosphate Isomerase Is a Potential Target in Cancer Due to Commonly Occurring Post-Translational Modifications.
Molecules
; 28(16)2023 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37630415
3.
The Giardial Arginine Deiminase Participates in Giardia-Host Immunomodulation in a Structure-Dependent Fashion via Toll-like Receptors.
Int J Mol Sci
; 23(19)2022 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36232855
4.
Multilevel Approach for the Treatment of Giardiasis by Targeting Arginine Deiminase.
Int J Mol Sci
; 22(17)2021 Aug 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-34502400
5.
Proton pump inhibitors drastically modify triosephosphate isomerase from Giardia lamblia at functional and structural levels, providing molecular leads in the design of new antigiardiasic drugs.
Biochim Biophys Acta
; 1860(1 Pt A): 97-107, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26518348
6.
Mutations of Glucose-6-Phosphate Dehydrogenase Durham, Santa-Maria and A+ Variants Are Associated with Loss Functional and Structural Stability of the Protein.
Int J Mol Sci
; 16(12): 28657-68, 2015 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26633385
7.
The oxidative fermentation of ethanol in Gluconacetobacter diazotrophicus is a two-step pathway catalyzed by a single enzyme: alcohol-aldehyde Dehydrogenase (ADHa).
Int J Mol Sci
; 16(1): 1293-311, 2015 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25574602
8.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
Biochim Biophys Acta
; 1834(12): 2702-11, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24056040
9.
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Antimicrob Agents Chemother
; 58(12): 7072-82, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25223993
10.
The stability of G6PD is affected by mutations with different clinical phenotypes.
Int J Mol Sci
; 15(11): 21179-201, 2014 Nov 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-25407525
11.
Naturally occurring deamidated triosephosphate isomerase is a promising target for cell-selective therapy in cancer.
Sci Rep
; 12(1): 4028, 2022 03 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35256749
12.
Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: a study for antiparasitic drug design.
Proteins
; 79(9): 2711-24, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21786322
13.
Deamidated Human Triosephosphate Isomerase is a Promising Druggable Target.
Biomolecules
; 10(7)2020 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32679775
14.
Delivery mode-associated gut microbiota in the first 3 months of life in a country with high obesity rates: A descriptive study.
Medicine (Baltimore)
; 99(40): e22442, 2020 Oct 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33019428
15.
Unraveling the mechanisms of tryptophan fluorescence quenching in the triosephosphate isomerase from Giardia lamblia.
Biochim Biophys Acta
; 1784(11): 1493-500, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18620084
16.
Species-specific inhibition of Giardia lamblia triosephosphate isomerase by localized perturbation of the homodimer.
Mol Biochem Parasitol
; 157(2): 179-86, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18077010
17.
Disulfide bridges in the mesophilic triosephosphate isomerase from Giardia lamblia are related to oligomerization and activity.
J Mol Biol
; 365(3): 752-63, 2007 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-17095008
18.
First characterization of a microsporidial triosephosphate isomerase and the biochemical mechanisms of its inactivation to propose a new druggable target.
Sci Rep
; 8(1): 8591, 2018 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29872223
19.
Morphological Studies of Nucleologenesis in Giardia lamblia.
Anat Rec (Hoboken)
; 299(5): 549-56, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26833978
20.
Allosteric Interactions by p53 mRNA Govern HDM2 E3 Ubiquitin Ligase Specificity under Different Conditions.
Mol Cell Biol
; 36(16): 2195-205, 2016 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27215386