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1.
Treatment with anti-gremlin 1 antibody ameliorates chronic hypoxia/SU5416-induced pulmonary arterial hypertension in mice.
Am J Pathol
; 183(5): 1461-73, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24160323
2.
Applications and challenges in designing VHH-based bispecific antibodies: leveraging machine learning solutions.
MAbs
; 16(1): 2341443, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38666503
3.
Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.
Am J Respir Cell Mol Biol
; 42(4): 472-81, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19556605
4.
Nanobodies® as inhaled biotherapeutics for lung diseases.
Pharmacol Ther
; 169: 47-56, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27373507
5.
In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
Cell Signal
; 17(9): 1158-73, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15905070
6.
Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats.
Neuropharmacology
; 49 Suppl 1: 167-78, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16023685
7.
Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays.
Chem Biol
; 11(10): 1361-72, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15489163
8.
Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene.
Biochem J
; 380(Pt 2): 371-84, 2004 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15025561
9.
Nanobodies and their Use in GPCR Drug Discovery.
Curr Top Med Chem
; 15(24): 2543-57, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26126902
10.
Non-nicotinic neuropharmacological strategies for nicotine dependence: beyond bupropion.
Drug Discov Today
; 8(22): 1025-34, 2003 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14690633
11.
Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).
Br J Pharmacol
; 136(3): 421-33, 2002 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12023945
12.
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.
J Biol Chem
; 280(39): 33178-89, 2005 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-16030021
13.
Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter.
J Biol Chem
; 277(39): 35980-9, 2002 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-12121997
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