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1.
Disruption of memory B-cell trafficking by belimumab in patients with systemic lupus erythematosus.
Rheumatology (Oxford)
; 2024 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38775637
2.
A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes.
Diabetologia
; 64(2): 313-324, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33145642
3.
Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's syndrome.
Rheumatology (Oxford)
; 60(5): 2396-2408, 2021 05 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33221921
4.
Epigenetically quantified immune cells in salivary glands of Sjögren's syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology.
Rheumatology (Oxford)
; 59(2): 335-343, 2020 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31325310
5.
Target engagement and cellular fate of otelixizumab: a repeat dose escalation study of an anti-CD3ε mAb in new-onset type 1 diabetes mellitus patients.
Br J Clin Pharmacol
; 85(4): 704-714, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30566758
6.
Anti-IL-7 receptor α monoclonal antibody (GSK2618960) in healthy subjects - a randomized, double-blind, placebo-controlled study.
Br J Clin Pharmacol
; 85(2): 304-315, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30161291
7.
A CD3-specific antibody reduces cytokine production and alters phosphoprotein profiles in intestinal tissues from patients with inflammatory bowel disease.
Gastroenterology
; 147(1): 172-83, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24704524
8.
Temporal pharmacokinetic/pharmacodynamic interaction between human CD3ε antigen-targeted monoclonal antibody otelixizumab and CD3ε binding and expression in human peripheral blood mononuclear cell static culture.
J Pharmacol Exp Ther
; 355(2): 199-205, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26341624
9.
Differential response of regulatory and conventional CD4⺠lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action?
J Immunol
; 191(7): 3694-704, 2013 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23986534
10.
Population model-based analysis of the memory B-cell response following belimumab therapy in the treatment of systemic lupus erythematosus.
CPT Pharmacometrics Syst Pharmacol
; 12(4): 462-473, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36852495
11.
A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol.
Trials
; 24(1): 180, 2023 Mar 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36906660
12.
A randomized, phase II study of sequential belimumab and rituximab in primary Sjögren's syndrome.
JCI Insight
; 7(23)2022 12 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36477362
13.
Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren's syndrome is associated with B cell hyperactivity and type I interferon activity.
RMD Open
; 6(2)2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32540951
14.
Impact of both donor and recipient strains on cardiac allograft survival after blockade of the CD40-CD154 costimulatory pathway.
Transplantation
; 74(5): 740-3, 2002 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12352896
15.
Induced CD8+FoxP3+ Treg cells in rheumatoid arthritis are modulated by p38 phosphorylation and monocytes expressing membrane tumor necrosis factor α and CD86.
Arthritis Rheumatol
; 66(10): 2694-705, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24980778
16.
Comparison of single, homologous prime-boost and heterologous prime-boost immunization strategies against H5N1 influenza virus in a mouse challenge model.
Vaccine
; 28(3): 650-6, 2010 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-19896446
17.
Seasonal influenza vaccine elicits heterosubtypic immunity against H5N1 that can be further boosted by H5N1 vaccination.
Vaccine
; 28(7): 1778-85, 2010 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-20018265
18.
Different levels of immunogenicity of two strains of Fowlpox virus as recombinant vaccine vectors eliciting T-cell responses in heterologous prime-boost vaccination strategies.
Clin Vaccine Immunol
; 13(7): 747-57, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16829611
19.
Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapy.
J Immunol
; 169(10): 5401-4, 2002 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12421913
20.
Dependency of direct pathway CD4+ T cells on CD40-CD154 costimulation is determined by nature and microenvironment of primary contact with alloantigen.
J Immunol
; 172(4): 2163-70, 2004 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14764682
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