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1.

CD40L modulates CD4⁺ T-cell activation through receptor for activated C kinase 1.

van Os, Bram W; Vos, Winnie G; Bosmans, Laura A; van Tiel, Claudia M; Toom, Myrthe den; Beckers, Linda; Admiraal, Merel; Hoeksema, Marten A; de Winther, Menno P; Lutgens, Esther.

Eur J Immunol ; 53(12): e2350520, 2023 12.

Artículo en Inglés | MEDLINE | ID: mdl-37683186

2.

'Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity.

Lith, Sanne C; van Os, Bram W; Seijkens, Tom T P; de Vries, Carlie J M.

Eur J Immunol ; 50(11): 1643-1652, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-33063848

3.

Disruption of circadian rhythm by alternating light-dark cycles aggravates atherosclerosis development in APOE*3-Leiden.CETP mice.

Schilperoort, Maaike; van den Berg, Rosa; Bosmans, Laura A; van Os, Bram W; Dollé, Martijn E T; Smits, Noortje A M; Guichelaar, Teun; van Baarle, Debbie; Koemans, Lotte; Berbée, Jimmy F P; Deboer, Tom; Meijer, Johanna H; de Vries, Margreet R; Vreeken, Dianne; van Gils, Janine M; Willems van Dijk, Ko; van Kerkhof, Linda W M; Lutgens, Esther; Biermasz, Nienke R; Rensen, Patrick C N; Kooijman, Sander.

J Pineal Res ; 68(1): e12614, 2020 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-31599473

4.

SPARCing the clot.

van Os, Bram; Lutgens, Esther.

Blood ; 137(11): 1441-1442, 2021 03 18.

Artículo en Inglés | MEDLINE | ID: mdl-33734343

5.

Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage.

Hiemstra, Steven; Niemeijer, Marije; Koedoot, Esmee; Wink, Steven; Klip, Janna E; Vlasveld, Matthijs; de Zeeuw, Elisabeth; van Os, Bram; White, Andrew; Water, Bob van de.

Chem Res Toxicol ; 30(4): 923-933, 2017 04 17.

Artículo en Inglés | MEDLINE | ID: mdl-27982581

6.

T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.

Vos, Winnie G; van Os, Bram W; den Toom, Myrthe; Beckers, Linda; van Roomen, Cindy P A A; van Tiel, Claudia M; Mohapatra, Bhopal C; Band, Hamid; Nitz, Katrin; Weber, Christian; Atzler, Dorothee; de Winther, Menno P J; Bosmans, Laura A; Lutgens, Esther; Seijkens, Tom T P.

Front Immunol ; 15: 1297893, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38504977

7.

Doxycycline induces mitochondrial dysfunction in aortic smooth muscle cells.

Yap, Carmen; Wanga, Shaynah; Wüst, Rob C I; van Os, Bram W; Pijls, Maud M E; Keijzer, Sofie; van Zanten, Eva; Koolbergen, David R; Driessen, Antoine H G; Balm, Ron; Yeung, Kak Khee; de Vries, Carlie J M; Houtkooper, Riekelt H; Lindeman, Jan H N; de Waard, Vivian.

Vascul Pharmacol ; 154: 107279, 2024 03.

Artículo en Inglés | MEDLINE | ID: mdl-38272196

8.

Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis.

van Os, Bram W; Kusters, Pascal J H; den Toom, Myrthe; Beckers, Linda; van Tiel, Claudia M; Vos, Winnie G; de Jong, Elize; Kieser, Arnd; van Roomen, Cindy; Binder, Christoph J; Reiche, Myrthe E; de Winther, Menno P; Bosmans, Laura A; Lutgens, Esther.

Front Cardiovasc Med ; 10: 1171764, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37215541

9.

Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state.

Bosmans, Laura A; van Tiel, Claudia M; Aarts, Suzanne A B M; Willemsen, Lisa; Baardman, Jeroen; van Os, Bram W; Toom, Myrthe den; Beckers, Linda; Ahern, David J; Levels, Johannes H M; Jongejan, Aldo; Moerland, Perry D; Verberk, Sanne G S; den Bossche, Jan van; de Winther, Menno M P J; Weber, Christian; Atzler, Dorothee; Monaco, Claudia; Gerdes, Norbert; Shami, Annelie; Lutgens, Esther.

Cardiovasc Res ; 119(5): 1146-1160, 2023 05 22.

Artículo en Inglés | MEDLINE | ID: mdl-35587037

10.

Hyperlipidaemia elicits an atypical, T helper 1-like CD4⁺ T-cell response: a key role for very low-density lipoprotein.

van Os, Bram W; Vos, Winnie G; Bosmans, Laura A; van Tiel, Claudia M; Lith, Sanne C; den Toom, Myrthe S; Beckers, Linda; Levels, Johannes H M; van Wouw, Suzanne A E; Zelcer, Noam; Zaal, Esther A; Berkers, Celia R; van der Lest, Chris H A; Helms, J Bernd; Weber, Christian; Atzler, Dorothee; de Winther, Menno P J; Baardman, Jeroen; Lutgens, Esther.

Eur Heart J Open ; 3(2): oead013, 2023 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-36969380

11.

Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗3-Leiden.CETP mice.

In Het Panhuis, Wietse; Schönke, Milena; Modder, Melanie; Tom, Hannah E; Lalai, Reshma A; Pronk, Amanda C M; Streefland, Trea C M; van Kerkhof, Linda W M; Dollé, Martijn E T; Depuydt, Marie A C; Bot, Ilze; Vos, Winnie G; Bosmans, Laura A; van Os, Bram W; Lutgens, Esther; Rensen, Patrick C N; Kooijman, Sander.

EBioMedicine ; 93: 104680, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-37356205

12.

Targeting cytokines and immune checkpoints in atherosclerosis with monoclonal antibodies.

Lutgens, Esther; Joffre, Jeremie; van Os, Bram; Ait-Oufella, Hafid.

Atherosclerosis ; 335: 98-109, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34593238

13.

Genotype-phenotype correlation in pseudoxanthoma elasticum.

Bartstra, Jonas W; Risseeuw, Sara; de Jong, Pim A; van Os, Bram; Kalsbeek, Lianne; Mol, Chris; Baas, Annette F; Verschuere, Shana; Vanakker, Olivier; Florijn, Ralph J; Hendrikse, Jeroen; Mali, Willem; Imhof, Saskia; Ossewaarde-van Norel, Jeannette; van Leeuwen, Redmer; Spiering, Wilko.

Atherosclerosis ; 324: 18-26, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33812167

14.

Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction.

Reiche, Myrthe E; den Toom, Myrthe; Willemsen, Lisa; van Os, Bram; Gijbels, Marion J J; Gerdes, Norbert; Aarts, Suzanne A B M; Lutgens, Esther.

BMJ Open Diabetes Res Care ; 7(1): e000829, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31908798

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