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1.
Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med
; 11(482)2019 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30842315
2.
Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.
Cell Cycle
; 17(4): 468-478, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29157092
3.
Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
PLoS One
; 12(8): e0180541, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28767654
4.
Direct control of caveolin-1 expression by FOXO transcription factors.
Biochem J
; 385(Pt 3): 795-802, 2005 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15458387
5.
ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases.
Sci Signal
; 9(415): ra18, 2016 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26884600
6.
Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.
Cancer Res
; 75(18): 3842-52, 2015 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26294215
7.
Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10.
Cancer Res
; 75(8): 1668-74, 2015 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25681273
8.
Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.
Cancer Res
; 74(4): 1153-65, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24247721
9.
Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities.
Curr Drug Targets
; 15(1): 80-9, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24387333
10.
Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth.
Cancer Biol Ther
; 13(12): 1185-94, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22892846
11.
Novel common integration sites targeted by mouse mammary tumor virus insertion in mammary tumors have oncogenic activity.
PLoS One
; 6(11): e27425, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22087314
12.
Binding of protein kinase B to the plakin family member periplakin.
J Cell Sci
; 115(Pt 20): 3957-66, 2002 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12244133
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