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1.
Stimulation of S1PR5 with A-971432, a selective agonist, preserves blood-brain barrier integrity and exerts therapeutic effect in an animal model of Huntington's disease.
Hum Mol Genet
; 27(14): 2490-2501, 2018 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29688337
2.
Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier.
J Neuroinflammation
; 9: 133, 2012 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-22715976
3.
Isoform- and cell-state-specific lipidation of ApoE in astrocytes.
Cell Rep
; 38(9): 110435, 2022 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35235798
4.
The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats.
Addict Biol
; 16(1): 108-15, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20579001
5.
Critical evaluation of the use of extinction paradigms for the assessment of opioid-induced conditioned place preference in rats.
Pharmacology
; 87(5-6): 286-96, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21577043
6.
Quantitative Systems Pharmacology Model for Alzheimer Disease Indicates Targeting Sphingolipid Dysregulation as Potential Treatment Option.
CPT Pharmacometrics Syst Pharmacol
; 7(11): 759-770, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30207429
7.
Anticonvulsant effects of structurally diverse GABA(B) positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model.
Neuropharmacology
; 101: 358-69, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26471422
8.
Gene - environment interactions determine the individual variability in cocaine self-administration.
Neuropharmacology
; 48(5): 685-95, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15814103
9.
Individual differences in drug dependence in rats: the role of genetic factors and life events.
Eur J Pharmacol
; 526(1-3): 251-8, 2005 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-16253227
10.
Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders.
J Med Chem
; 58(23): 9154-70, 2015 Dec 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26509640
11.
Dissociation of rewarding, anti-aversive and anti-nociceptive effects of different classes of anti-nociceptives in the rat.
Eur J Pain
; 15(3): 299-305, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20801699
12.
2-Methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates ketamine and heroin reward as assessed by acquisition, extinction, and reinstatement of conditioned place preference in the rat.
Eur J Pharmacol
; 606(1-3): 94-101, 2009 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19210976
13.
The mGlu5 receptor antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) supports intravenous self-administration and induces conditioned place preference in the rat.
Eur J Pharmacol
; 607(1-3): 114-20, 2009 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19326478
14.
Differential effects of morphine on the affective and the sensory component of carrageenan-induced nociception in the rat.
Pain
; 136(3): 373-379, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17825490
15.
Effect of 2-methyl-6-(phenylethynyl) pyridine on intravenous self-administration of ketamine and heroin in the rat.
Behav Pharmacol
; 18(8): 717-24, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17989509
16.
Expression of cocaine-induced conditioned place preference in apomorphine susceptible and unsusceptible rats.
Behav Pharmacol
; 17(4): 331-40, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16914951
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