Detalles de la búsqueda
1.
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Nature
; 585(7824): 303-308, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32879488
2.
Novel benzimidazole-linked (thio)barbiturates as non-hydroxamate HDAC6 inhibitors targeting leukemia: Design, synthesis, and structure-activity relationship.
Arch Pharm (Weinheim)
; 356(6): e2200433, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36942938
3.
Photomotor Responses in Zebrafish and Electrophysiology Reveal Varying Interactions of Anesthetics Targeting Distinct Sites on γ-Aminobutyric Acid Type A Receptors.
Anesthesiology
; 137(5): 568-585, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36018576
4.
Electrochemical thiocyanation of barbituric acids.
Org Biomol Chem
; 20(17): 3629-3636, 2022 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35420113
5.
Discovery of cinnamamide-barbiturate hybrids as a novel class of Nrf2 activator against myocardial ischemia/reperfusion injury.
Bioorg Chem
; 124: 105828, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35490584
6.
In vitro evaluation of the anticancer activity of barbituric/thiobarbituric acid-based chromene derivatives.
Mol Biol Rep
; 48(12): 7637-7646, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34741706
7.
Temporal effects of barbiturate coma on intracranial pressure and compensatory reserve in children with traumatic brain injury.
Acta Neurochir (Wien)
; 163(2): 489-498, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33341913
8.
Barbiturate derivatives for managing multifaceted oncogenic pathways: A mini review.
Drug Dev Res
; 82(3): 364-373, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33210368
9.
Effect of Selected Anionic and Cationic Drugs Affecting the Central Nervous System on Electrical Properties of Phosphatidylcholine Liposomes: Experiment and Theory.
Int J Mol Sci
; 22(5)2021 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33668791
10.
Novel N,N-dimethylbarbituric-pyridinium derivatives as potent urease inhibitors: Synthesis, in vitro, and in silico studies.
Bioorg Chem
; 95: 103529, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31884139
11.
Design and synthesis of some barbituric and 1,3-dimethylbarbituric acid derivatives: A non-classical scaffold for potential PARP1 inhibitors.
Bioorg Chem
; 104: 104198, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32920355
12.
1,2,3-Triazole-linked 5-benzylidene (thio)barbiturates as novel tyrosinase inhibitors and free-radical scavengers.
Arch Pharm (Weinheim)
; 353(10): e2000058, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32638438
13.
Molecular and Regulatory Mechanisms of Desensitization and Resensitization of GABAA Receptors with a Special Reference to Propofol/Barbiturate.
Int J Mol Sci
; 21(2)2020 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31952324
14.
Treatment with a New Barbituric Acid Derivative Exerts Antiproliferative and Antimigratory Effects against Sorafenib Resistance in Hepatocellular Carcinoma.
Molecules
; 25(12)2020 Jun 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32575795
15.
Monod-Wyman-Changeux Allosteric Shift Analysis in Mutant α1ß3γ2L GABAA Receptors Indicates Selectivity and Crosstalk among Intersubunit Transmembrane Anesthetic Sites.
Mol Pharmacol
; 95(4): 408-417, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30696720
16.
Cardioprotective effect of MMP-2-inhibitor-NO-donor hybrid against ischaemia/reperfusion injury.
J Cell Mol Med
; 23(4): 2836-2848, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30729745
17.
Determination of MIC Quality Control Ranges for the Novel Gyrase Inhibitor Zoliflodacin.
J Clin Microbiol
; 57(9)2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31315953
18.
In vitro antimicrobial combination testing of and evolution of resistance to the first-in-class spiropyrimidinetrione zoliflodacin combined with six therapeutically relevant antimicrobials for Neisseria gonorrhoeae.
J Antimicrob Chemother
; 74(12): 3521-3529, 2019 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31730160
19.
Expeditious Synthesis of C-Glycosyl Barbiturate Ligands of Bacterial Lectins: From Monomer Design to Glycoclusters and Glycopolymers.
Bioconjug Chem
; 30(3): 647-656, 2019 03 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30590917
20.
Probing the high potency of pyrazolyl pyrimidinetriones and thioxopyrimidinediones as selective and efficient non-nucleotide inhibitors of recombinant human ectonucleotidases.
Bioorg Chem
; 88: 102893, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30986550