Detalles de la búsqueda
1.
Development of benzimidazole derivatives as efficient matrices for the analysis of acidic small-molecule compounds using matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry in negative ion mode.
Rapid Commun Mass Spectrom
; 38(13): e9751, 2024 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38680091
2.
A highly sensitive spectrofluorimetric method for the determination of bilastine in human plasma: Application of content uniformity testing.
Luminescence
; 39(7): e4816, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38965898
3.
A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma-Application to a Pharmacokinetic Study.
Molecules
; 28(1)2022 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615272
4.
Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo.
J Pharmacol Exp Ther
; 376(3): 436-443, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33376150
5.
A Phase 1 study of BAL101553, a novel tumor checkpoint controller targeting microtubules, administered as 48-h infusion in adult patients with advanced solid tumors.
Invest New Drugs
; 38(4): 1067-1076, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31471863
6.
Drug-drug interactions of newly approved small molecule inhibitors for acute myeloid leukemia.
Ann Hematol
; 99(9): 1989-2007, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32683457
7.
Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats.
Biol Pharm Bull
; 43(3): 384-392, 2020 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31685755
8.
Simultaneous quantification of abemaciclib and letrozole in rat plasma: method development, validation and pharmacokinetic application.
Biomed Chromatogr
; 34(6): e4825, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-32166756
9.
Micellar-based spectrofluorimetric method for the selective determination of ledipasvir in the presence of sofosbuvir: application to dosage forms and human plasma.
Luminescence
; 35(4): 486-492, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-31869004
10.
Development and validation of liquid chromatography-electrospray-tandem mass spectrometry method for determination of flibanserin in human plasma: Application to pharmacokinetic study on healthy female volunteers.
Biomed Chromatogr
; 33(8): e4545, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30937940
11.
A simple, rapid and fully validated HPLC method for simultaneous quantitative bio-analysis of rosuvastatin and candesartan in rat plasma: Application to pharmacokinetic interaction study.
Biomed Chromatogr
; 33(10): e4607, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31141832
12.
Evaluation of gender difference in pharmacokinetics of Candesartan cilexetil in the fasted state by RP-HPLC: A single dose comparative study.
Pak J Pharm Sci
; 32(3): 1019-1024, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-31278715
13.
Effects of Renal Impairment and Hemodialysis on the Pharmacokinetics and Safety of the Glecaprevir and Pibrentasvir Combination in Hepatitis C Virus-Negative Subjects.
Antimicrob Agents Chemother
; 62(3)2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29263061
14.
Idarucizumab for Dabigatran Reversal.
N Engl J Med
; 373(6): 511-20, 2015 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26095746
15.
Population pharmacokinetics of the MEK inhibitor selumetinib and its active N-desmethyl metabolite: data from 10 phase I trials.
Br J Clin Pharmacol
; 84(1): 52-63, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-28833380
16.
Ledipasvir and tenofovir drug interaction in human immunodeficiency virus-hepatitis C virus coinfected patients: Impact on tenofovir trough concentrations and renal safety.
Br J Clin Pharmacol
; 84(2): 404-409, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29028125
17.
Pharmacokinetic evaluation of daclatasvir and ledipasvir in healthy volunteers using a validated highly sensitive spectrofluorimetric method.
Luminescence
; 33(6): 1094-1100, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-30047624
18.
Pharmacokinetic assessment of the monepantel plus oxfendazole combined administration in dairy cows.
J Vet Pharmacol Ther
; 41(2): 292-300, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29139145
19.
Development and validation of HPLC method for the determination of Candesartan in human plasma.
Pak J Pharm Sci
; 31(6): 2323-2327, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30473499
20.
Effects of cytochrome P450 (CYP3A4 and CYP2C19) inhibition and induction on the exposure of selumetinib, a MEK1/2 inhibitor, in healthy subjects: results from two clinical trials.
Eur J Clin Pharmacol
; 73(2): 175-184, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27889832