Detalles de la búsqueda
1.
Pharmacokinetic/Pharmacodynamic Assessment of the Structural Refinement of Clopidogrel Focusing on the Balance between Bioactivation and Deactivation.
Drug Metab Dispos
; 52(7): 654-661, 2024 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38729662
2.
Use of the VerifyNow point of care assay to assess the pharmacodynamic effects of loading and maintenance dose regimens of prasugrel and ticagrelor.
J Thromb Thrombolysis
; 51(3): 741-747, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33582955
3.
Solid self nano-emulsifying system for the enhancement of dissolution and bioavailability of Prasugrel HCl: in vitro and in vivo studies.
Pharm Dev Technol
; 26(9): 1021-1033, 2021 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-34435939
4.
Concomitant use of drugs known to cause interactions with oral antiplatelets-polypharmacy in acute coronary syndrome outpatients in Finland.
Eur J Clin Pharmacol
; 76(2): 257-265, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31773191
5.
Pharmacodynamic assessment of prasugrel and clopidogrel in patients with non-cardioembolic stroke: a multicenter, randomized, active-control clinical trial.
J Thromb Thrombolysis
; 49(1): 10-17, 2020 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-31643039
6.
Pharmacodynamic Comparison of Prasugrel Versus Ticagrelor in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease: The OPTIMUS (Optimizing Antiplatelet Therapy in Diabetes Mellitus)-4 Study.
Circulation
; 134(11): 780-92, 2016 Sep 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-27559041
7.
Time course of the antiplatelet effect after switching to clopidogrel from initial prasugrel therapy in patients with acute coronary syndrome.
Heart Vessels
; 32(12): 1432-1438, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28685204
8.
Pharmacodynamic Assessment of Platelet Reactivity After a Loading Dose of Prasugrel or Clopidogrel in Patients With ST-Segment Elevation Myocardial Infarction.
Circ J
; 80(12): 2520-2527, 2016 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-27725493
9.
PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes.
J Thromb Thrombolysis
; 41(3): 374-83, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26573179
10.
Prasugrel 5 mg inhibits platelet P-selectin and GPIIb-IIIa expression in very elderly and non elderly: results from the GENERATIONS trial, a pharmacodynamic study in stable CAD patients.
J Thromb Thrombolysis
; 42(3): 369-75, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27165280
11.
Effect of grapefruit juice on the bioactivation of prasugrel.
Br J Clin Pharmacol
; 80(1): 139-45, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25557052
12.
Chewed or Crushed Administration of Adenosine Diphosphate Receptor Inhibitors in Acute Coronary Syndromes: a Systematic Review and Meta-analysis of Randomized Controlled Trials.
Cardiovasc Drugs Ther
; 34(1): 139-142, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31485881
13.
COMparison of Platelet reactivity following prAsugrel and ticagrelor loading dose in ST-Segment elevation myocardial infarctION patients: The COMPASSION study.
Platelets
; 26(6): 570-2, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25275609
14.
Prevalence of CYP2C19 alleles, pharmacokinetic and pharmacodynamic variation of clopidogrel and prasugrel in Bangladeshi population.
Clin Exp Pharmacol Physiol
; 42(5): 451-7, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25800075
15.
VERifyNow in DIabetes high-on-treatment platelet reactivity: a pharmacodynamic study on switching from clopidogrel to prasugrel.
Acta Cardiol
; 70(6): 728-34, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26717223
16.
Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of Prasugrel in Healthy Male Volunteers.
Clin Pharmacol Drug Dev
; 12(1): 21-29, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36251178
17.
Facilitation Through Aggrastat or Cangrelor Bolus and Infusion Over PrasugreL: a MUlticenter Randomized Open-label Trial in PatientS with ST-elevation Myocardial InFarction Referred for PrimAry PercutaneouS InTERvention (FABOLUS FASTER) Trial: Design and Rationale : The FABOLUS FASTER Trial.
J Cardiovasc Transl Res
; 14(1): 110-119, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32096064
18.
Ticagrelor and prasugrel in acute coronary syndrome: a single-arm crossover platelet reactivity study.
J Cardiovasc Med (Hagerstown)
; 22(9): 686-692, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34280175
19.
Pharmacokinetic/pharmacodynamic modeling of drug interactions at the P2Y12 receptor between selatogrel and oral P2Y12 antagonists.
CPT Pharmacometrics Syst Pharmacol
; 10(7): 735-747, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33955698
20.
Pharmacokinetics and Pharmacodynamics of Approved and Investigational P2Y12 Receptor Antagonists.
Clin Pharmacokinet
; 59(5): 545-566, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32056160