Novel 2-Nitroimidazole and Imidazooxazole Derivatives and their Activity against Trypanosoma cruzi and Mycobacterium tuberculosis

Faria, Jessica V; Passos, Fernanda P Z; Costa, Paulo H A da; Oliveira, Andressa P de; Cruz, Yasmin O D da; Castelo-Branco, Frederico S; Lourenço, Maria C S; Murta, Silvane Maria Fonseca; Sales Junior, Policarpo Ademar; Bernardino, Alice M R; Bastos, Monica M; Boechat, Nubia.
Artículo en Inglés | ARCA | ID: arc-56492

Documentos relacionados

  1. Exploring Geometrical, Electronic and Spectroscopic Properties of 2-Nitroimidazole-Based Radiopharmaceuticals via Computational Chemistry Methods.
  2. Cu-Catalyzed Chan-Evans-Lam Coupling Reactions of 2-Nitroimidazole with Aryl Boronic Acids: An Effort toward New Bioactive Agents against S. pneumoniae.
  3. Anti-<i>Trypanosoma cruzi</i> Activity, Mutagenicity, Hepatocytotoxicity and Nitroreductase Enzyme Evaluation of 3-Nitrotriazole, 2-Nitroimidazole and Triazole Derivatives.
  4. Discovery and characterization of antimycobacterial nitro-containing compounds with distinct mechanisms of action and <i>in vivo</i> efficacy.
  5. New 2-nitroimidazole-N-acylhydrazones, analogs of benznidazole, as anti-Trypanosoma cruzi agents.
  6. Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.
  7. Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi <i>In Vitro</i> and <i>In Vivo</i>.
  8. Transesterification of RNA model induced by novel dinuclear copper (II) complexes with bis-tridentate imidazole derivatives.
  9. Novel 2-Nitroimidazole and Imidazooxazole Derivatives and their Activity against Trypanosoma cruzi and Mycobacterium tuberculosis.
  10. Efficacy of Novel Pyrazolone Phosphodiesterase Inhibitors in Experimental Mouse Models of Trypanosoma cruzi.