Structural and functional analysis of a potent sarbecovirus neutralizing antibody

Dora Pinto; Young-Jun Park; Martina Beltramello; Alexandra C. Walls; M. Alejandra Tortorici; Siro Bianchi; Stefano Jaconi; Katja Culap; Fabrizia Zatta; Anna De Marco; Alessia Peter; Barbara Guarino; Roberto Spreafico; Elisabetta Cameroni; James Brett Case; Rita E. Chen; Colin Havenar-Daughton; Gyorgy Snell; Amalio Telenti; Herbert W. Virgin; Antonio Lanzavecchia; Michael S. Diamond; Katja Fink; David Veesler; Davide Corti.
Preprint en Inglés | PREPRINT-BIORXIV | ID: ppbiorxiv-023903

Documentos relacionados

  1. Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
  2. The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
  3. Structural and functional analysis of a potent sarbecovirus neutralizing antibody.
  4. Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
  5. Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
  6. Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity.
  7. Reduced neutralization and Fc effector function to Omicron subvariants in sera from SARS-CoV-1 survivors after two doses of CoronaVac plus one dose subunit vaccine.
  8. Broad Sarbecovirus Neutralizing Antibodies Obtained by Computational Design and Synthetic Library Screening.
  9. Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
  10. Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2.