High titers of multiple antibody isotypes against the SARS-CoV-2 spike receptor-binding domain and nucleoprotein associate with better neutralization.

Maria G Noval; Maria E Kaczmarek; Akiko Koide; Bruno A Rodriguez-Rodriguez; Ping Louie; Takuya Tada; Takamitsu Hattori; Tatyana Panchenko; Larizbeth A Romero; Kai Wen Teng; Andrew Bazley; Maren de Vries; Marie I Samanovic; Jeffrey N Weiser; Ioannis Aifantis; Joan Cangiarella; Mark J Mulligan; Ludovic Desvignes; Meike Dittmann; Nathaniel R Landau; Maria E Aguero-Rosenfeld; Shohei Koide; Kenneth A Stapleford Jr..
Preprint en Inglés | PREPRINT-BIORXIV | ID: ppbiorxiv-252353

Documentos relacionados

  1. Antibody isotype diversity against SARS-CoV-2 is associated with differential serum neutralization capacities.
  2. Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants.
  3. Exploring the immune evasion of SARS-CoV-2 variant harboring E484K by molecular dynamics simulations.
  4. Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants.
  5. Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants.
  6. SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency.
  7. A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike.
  8. A human coronavirus evolves antigenically to escape antibody immunity.
  9. Divergent Antibody Repertoires Found for Omicron versus Wuhan SARS-CoV-2 Strains Using Ig-MS.
  10. Development of a Rapid Live SARS-CoV-2 Neutralization Assay Based on a qPCR Readout.