Inhibiting LSD1 suppresses coronavirus-induced inflammation but spares innate antiviral activity

Luca Mazzarella; Fabio Santoro; Roberto Ravasio; Paul Massa; Simona Rodighiero; Elena Gaviln; Mauro Romanenghi; Bruno Duso; Emanuele Bonetti; Rani Pallavi; Deborah Trastulli; Isabella Pallavicini; Claudia Gentile; Tommaso Leonardi; Gabriele Buttinelli; Sebastiano Pasqualato; Angela Di Martino; Giorgio Fedele; Ilaria Schiavoni; Paola Stefanelli; Giuseppe Meroni; Christian Steinkuhler; Gianluca Fossati; Saverio Minucci; Pier Giuseppe Pelicci.
Preprint en Inglés | PREPRINT-BIORXIV | ID: ppbiorxiv-441948

Documentos relacionados

  1. Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses.
  2. Systemic Lupus Erythematosus Pathogenesis: Interferon and Beyond.
  3. Innate immunity and interferon in SARS-CoV-2 infection outcome.
  4. PCNA negatively regulates MITA through the autophagy pathway in miiuy croaker (Miichthys miiuy).
  5. Effective Interferon Lambda Treatment Regimen To Control Lethal MERS-CoV Infection in Mice.
  6. Differential beta-coronavirus infection dynamics in human bronchial epithelial organoids.
  7. The pathogenesis of coronavirus-19 disease.
  8. Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection.
  9. Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids.
  10. Adenovirus protein VII binds the A-box of HMGB1 to repress interferon responses.