Alzheimer's Disease
Lau, Lit-Fui.
Berlin, Heidelberg; Springer Berlin Heidelberg;
2008.
Monografía
en Inglés
| Bibliografia | ID: bib-350781
Alzheimer's disease (AD) is a neurodegenerativedisease that robs the minds of our elderly population.Approximately one in every eight adults over the age of 65 andnearly half of those over 85 are afflicted with this disease. Theaging population in developed societies will impose an everincreasing socioeconomic threat in the future. Current medicinesfor AD patients are mainly symptomatic treatments and a huge unmetmedical need exists to slow the progression of this disease. Agreat deal of research has been dedicated to understanding thepathogenesis of AD from which comes many ideas for intervening withits progression. Some of these ideas have been fast-tracked toclinical trials due to the availability of medicines with provenclinical efficacies for other diseases (e.g. atorvastatin,simvastatin, rosiglitazone and clioquinol) while others representnovel chemical entities (e.g. glycogen synthase kinase-3inhibitors). This volume will first review existing cholinesteraseinhibitors prescribed for AD patients followed by some targetmechanisms with ongoing clinical trials. It offers a glimpse ofwhat our future medicine cabinets may look like for AD patients. Italso provides an interesting read on why and how current medicinesfor other indications could potentially be used to treatAD.
Biblioteca responsable:
MX25.1
Ubicación: MX25.1
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