Liver involvement occurs in 0.2 to 3% of
patients with
syphilis. We
report three
patients with
liver involvement in
syphilis. A 52-year-old
male presenting with
erythema and malaise.
Laboratory showed a
gamma glutamyl transpeptidase (GGT) of 853 u/l, alkaline
phosphatases of 1,010 U/L and VDRL was positive.
Treatment with
penicillin resolved the
skin problem and normalized
liver enzymes. A
HIV positive 30-year-old
male in
peritoneal dialysis presenting with
itching, malaise and markedly elevated GGT and alkaline
phosphatases. VDRL was positive. He was treated with
penicillin with remission of symptoms and
enzyme normalization. A 43-year-old
male presenting with
erythema, malaise,
arthralgias and elevated GGT and alkaline
phosphatases. VDRL was positive and
treatment with
penicillin reverted symptoms and
laboratory abnormalities.